Antibiotic resistance

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Unknown (22890)
Genomics (5437)
Transcriptomics (1135)
Proteomics (381)
Metabolomics (126)
Other (32)
Models (14)
Genomic (2)
Multiomics (2)

Organisms

Homo sapiens (315)
Mus musculus (154)
Staphylococcus aureus (87)
Escherichia coli (76)
Pseudomonas aeruginosa (55)
Streptomyces coelicolor (26)
Saccharomyces cerevisiae (23)
Caenorhabditis elegans (22)
Candida albicans (18)
Sus scrofa (18)
Acinetobacter baumannii (17)
Enterococcus faecalis (17)
Pseudomonas aeruginosa PAO1 (17)
Rattus norvegicus (15)
Arabidopsis thaliana (14)
Streptococcus pneumoniae (13)
Bacillus subtilis (12)
Mycobacterium tuberculosis (11)
Bos taurus (11)
Drosophila melanogaster (10)
Streptomyces coelicolor A3(2) (10)
Enterococcus faecium (10)
Campylobacter jejuni (9)
Burkholderia cenocepacia (8)
Salmonella enterica (8)
Bacillus subtilis subsp. subtilis str. 168 (7)
Mycobacterium tuberculosis H37Rv (6)
Corynebacterium glutamicum ATCC 13032 (5)
Danio rerio (5)
Streptomyces venezuelae (4)

Organisms

Escherichia coli (260)
Klebsiella pneumoniae (100)
Staphylococcus aureus (93)
Pseudomonas aeruginosa (86)
Acinetobacter baumannii (74)
Homo sapiens (46)
soil metagenome (42)
Mus musculus (42)
wastewater metagenome (39)
Pandoraea pneumonica (30)
Salmonella enterica (22)
Bacteria (20)
Enterococcus faecalis (20)
46170 (18)
Escherichia coli K-12 (18)
human gut metagenome (18)
Campylobacter coli (17)
Escherichia coli str. K-12 substr. MG1655 (16)
Vibrio cholerae (16)
gut metagenome (16)
activated sludge metagenome (16)
Enterococcus faecium (15)
Enterobacter hormaechei (14)
mouse gut metagenome (13)
Campylobacter jejuni (11)
Helicobacter pylori (11)
Enterobacter cloacae (10)
Pseudomonas aeruginosa PAO1 (10)
Neisseria gonorrhoeae (10)
aquatic metagenome (10)

Repository

ENA (5350)
biostudies-arrayexpress (920)
geo (332)
pride (256)
MetaboLights (94)
iProX (57)
MassIVE (53)
MetabolomicsWorkbench (22)
BioModels (13)
EGA (12)
GNPS (10)
jPOST (7)
PanoramaPublic (4)
dbGaP (2)
EVA (1)
FAIRDOMHub (1)
PAXDB (1)

Tissue

Cell culture (51)
Epithelial cell (6)
Permanent cell line cell (6)
Prokaryotic cell (6)
Cecum (5)
Liver (5)
Cell suspension culture (4)
Bacterial cells (3)
Blood (3)
Intestine (2)
Feces (2)
Urine (2)
Culture condition:anaerobically-grown cell (2)
Feces (2)
Macrophage (2)
Monocyte (2)
Neutrophil (2)
Primary cell (2)
Whole body (2)
Bacterial protein (1)
Biofilm (1)
Blood (1)
Blood plasma (1)
Bone marrow (1)
CACO-2 cell (1)
Colon (1)
Embryonic stem cell (1)
Hepatocyte (1)
Leaf (1)
Leukocyte (1)

Disease

Antibiotic resistance (22)
Normal (4)
Breast cancer (2)
Bacterial infectious disease (2)
Colon cancer (2)
Gonorrhea (2)
Tuberculosis (2)
Primary acute lymphoblastic leukemia (1)
Pretreatment primary leukemia (1)
Chronic myelogenous leukemia (1)
B. dendrobatidis infection (1)
Hodgkin lymphoma, mixed cellularity, stage IV (1)
Infected (1)
Metarhizium anisopliae infected (1)
Melanoma (1)
T-cell acute lymphoblastic leukemia (1)
Euploid (1)
Obesity (1)
C. burnetii infected (1)
S enteritidis (1)
Control (1)
Cervix carcinoma (1)
Chronic bronchitis (1)
Colitis (1)
Congenital diarrhea (1)
Crohn's disease (1)
Cystic fibrosis (1)
Drug allergy (1)
Epidural abscess (1)
Hypersensitivity reaction type IV disease (1)

Technology Type

Mass Spectrometry (266)
Shotgun proteomics (145)
Mass spectrometry (63)
Bottom-up proteomics (50)
Data-dependent acquisition (38)
Mass spectrometry assay (27)
SWATH MS (18)
Data-independent acquisition (14)
NMR (12)
Top-down proteomics (11)
Gel-based experiment (10)
Affinity purification coupled with mass spectrometry proteomics (9)
EI (6)
Affinity proteomics (6)
HDMSE (5)
NMR spectroscopy (4)
ESI (4)
MSE (4)
SRM/MRM (4)
All-ion fragmentation (3)
Chemical cross-linking coupled with mass spectrometry proteomics (2)

Instrument Platform

NextSeq 500 (22)
Illumina NovaSeq 6000 (20)
Illumina HiSeq 2500 (17)
Illumina HiSeq 2000 (17)
Illumina HiSeq 4000 (10)
Illumina MiSeq (9)
Spectronic Helios Alpha UV-Vis spectrophotometer (5)
Ultracentrifuge (4)
ScanArray [PerkinElmer] (4)
Illumina NovaSeq X (4)
Illumina HiSeq 1500 (4)
ScanArray Lite [PerkinElmer] (3)
Bioanalyser (3)
NextSeq 2000 (3)
Complete Genomics (2)
Anaerobic workstation with airlock (2)
GenePix Professional 4200A [Axon Instruments] (2)
Variable Atmosphere Incubator (2)
Scanning hardware (2)
DNBSEQ-G400 (2)
NextSeq 550 (2)
Illumina DNA Prep sample preparation kits (Illumina Inc., San Diego, CA, USA). Final libraries concentrations and size were assessed with Quant-IT DNA Assay Kit and Agilent 4200 Tapestation System (Agilent Technologies, Milan, Italy), (1)
QIAamp DNA minikit, Qiagen, Germany (1)
HISAT2, TOPHAT2 (1)
High-performance computing workstation (1)
Protocol computer workstation running R statistical software (1)
Thermal cycler (PCR); Covaris ME220 focused ultrasonicator; magnetic separation rack; Agilent TapeStation system (D5000 and D1000 ScreenTape assays); Qubit fluorometer or equivalent; microcentrifuge. (1)
JANUS® G3 MDT automated liquid handling workstation (PerkinElmer); thermal cycler or incubator (42 °C); Zymo DNA Clean & Concentrator columns; AMPure XP magnetic bead purification system; magnetic separation rack. (1)
Multichannel pipettes or automated liquid handler; 384-well tissue culture plates; Class II biological safety cabinet; CO₂ incubator (37 °C, 5% CO₂). (1)
Quick-DNA 96 kit (Zymo) (1)

Publication Date

2010 (150)
2025 (135)
2012 (110)
2013 (109)
2024 (107)
2014 (101)
2026 (98)
2022 (95)
2011 (93)
2023 (92)
2021 (91)
2008 (88)
2015 (77)
2020 (70)
2016 (68)
2018 (56)
2019 (51)
2009 (50)
2007 (26)
2017 (23)
2005 (12)
2006 (6)
2004 (3)

UNIPROT ID/AC

3MGA_BACSU (1)
4OT_BACSU (1)
53DR_BACSU (1)
6PGDH_BACSU (1)
6PGD_BACSU (1)
6PGL_BACSU (1)
AADK_BACSU (1)
AAT1_BACSU (1)
AAT3_BACSU (1)
ABRB_BACSU (1)
ACCA_BACSU (1)
ACCC1_BACSU (1)
ACCC2_BACSU (1)
ACCD_BACSU (1)
ACDA_BACSU (1)
ACDB_BACSU (1)
ACDC_BACSU (1)
ACKA_BACSU (1)
ACNA_BACSU (1)
ACOA_BACSU (1)
ACOB_BACSU (1)
ACOC_BACSU (1)
ACOR_BACSU (1)
ACPK_BACSU (1)
ACPS_BACSU (1)
ACP_BACSU (1)
ACSA_BACSU (1)
ACUB_BACSU (1)
ACUC_BACSU (1)
ADAA_BACSU (1)

CHEBI ID

CHEBI:33282 (1)
CHEBI:57887 (1)
CHEBI:75989 (1)
CHEBI:30849 (1)
CHEBI:60083 (1)
CHEBI:71674 (1)
CHEBI:27667 (1)
CHEBI:61166 (1)
CHEBI:58336 (1)
CHEBI:58225 (1)
CHEBI:57822 (1)
CHEBI:61931 (1)
CHEBI:61933 (1)
CHEBI:46911 (1)
CHEBI:26689 (1)
CHEBI:57684 (1)
CHEBI:58145 (1)
CHEBI:48095 (1)
CHEBI:60374 (1)
CHEBI:22191 (1)
CHEBI:58557 (1)
CHEBI:57809 (1)
CHEBI:16037 (1)
CHEBI:58722 (1)
CHEBI:2411 (1)
CHEBI:44245 (1)
CHEBI:64834 (1)
CHEBI:10965 (1)
CHEBI:58694 (1)
CHEBI:17767 (1)

Metabolite Name

Adenosine (28)
Uridine (27)
Adenine (25)
Succinic acid (23)
Uracil (21)
Guanosine (21)
L-Phenylalanine (21)
Citric acid (20)
Thymine (20)
L-Tyrosine (20)
L-Proline (19)
Inosine (19)
Fumaric acid (18)
Palmitic acid (18)
Hypoxanthine (18)
Ornithine (17)
L-Threonine (17)
Cytosine (17)
L-Tryptophan (17)
Cytidine (17)
Stearic acid (16)
Dodecanoic acid (16)
Benzoic acid (15)
Heptadecanoic acid (15)
Guanine (15)
Xanthosine (15)
Oxalic acid (14)
L-Alanine (14)
Betaine (14)
L-Asparagine (14)

First Public Date

2025 (940)
2024 (886)
2026 (681)
2023 (490)
2022 (402)
2021 (396)
2020 (355)
2019 (279)
2018 (194)
2013 (192)
2017 (171)
2014 (145)
2016 (110)
2015 (98)
2012 (7)
2011 (4)

Modelling Approach

Constraint-based model (9)
Computational model (3)
Steady-state model (1)

Lab affiliation

Bioplatforms Australia (9)
Department of Clinical Microbiology, Sahlgrenska University Hospital, Gothenburg, Sweden (3)
Department of Medical Biochemistry and Microbiology, Uppsala University, Box 582, 75123, Uppsala, Sweden (3)
EDyP (3)
Genomics Research Center, Academia Sinica, Taipei, 11529 Taiwan (3)
University of Greifswald, Institute of Microbiology, Department of Microbial Physiology and Molecular Biology (3)
Advanced Water Management Centre, The University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia (2)
Biozentrum, University of Basel, 4056 Basel, Switzerland (2)
Chemical and Biological Engineering, The Hong Kong University of Science and Technology (HKUST) (2)
Department of Chemistry and Bioscience, Aalborg University, Fredrik Bajers Vej 7H, DK-9220, Aalborg East, Denmark (2)
Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia. (2)
Jinan University (2)
Lab. Neuro-oncologie en klinische en kanker proteomics Department of Neurology Erasmus MC (2)
Lanzhou University, Lanzhou, Gansu, China (2)
Max Perutz Labs, Vienna, Austria (2)
School of Biological and Behavioural Sciences Queen Mary University of London (2)
-Centre of Microbial and Plant Genetics; KU Leuven; Leuven, 3000; Belgium -Center for Microbiology; VIB-KU Leuven; Leuven, 3000; Belgium (1)
1 Centre of Microbial and Plant Genetics; KU Leuven; Leuven, 3000; Belgium 2 Center for Microbiology; VIB-KU Leuven; Leuven, 3000; Belgium (1)
1. Department of Paediatrics, University Hospital of North Norway, Tromsø, Norway 2 Paediatric Research Group, Department of Clinical Medicine, Faculty of Health Sciences, UiT- The Arctic University of Norway, Tromsø, Norway. (1)
1. Istitituto Sperimentale Italiano L. Spallanzani,Milano, Italy; 2. Dipartimento di Scienze Veterinarie e Sanità Pubblica, Università degli Studi di Milano, Milano, Italy. (1)
1Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, DK-2800 Lyngby, Denmark (1)
Advanced Water Management Centre, The University of Queensland (1)
Advanced Water Management Centre, The University of Queensland, Australia (1)
Advanced Water Management Centre, The University of Queensland, St. Lucia, Brisbane, Queensland, Australia, 4072 (1)
Agence Nationale de Sécurité Sanitaire (anses) ANSES – Laboratoire de Fougères Unité Toxicologie des contaminants Plateforme PROMETHEE 10 B rue Claude Bourgelat – Javené - CS 40608 35306 FOUGERES Cedex +33 (0)2 56 65 00 68 (1)
Applied Microbiology, Faculty of Biology and Biotechnology, Ruhr University Bochum, 44780 Bochum, Germany (1)
Associate Professor in Proteomics, Head of Proteomics, Centre for Proteomic Research, University of Southampton, UK (1)
Associate Professor | Department of Pharmaceutical Sciences | College of Pharmacy | Oregon State University (1)
Associate Professor, School of Biological Sciences, University of Southampton (1)
Associate Professor, Whitehead Institute for Biomedical Research and Massachusetts Institute for Technology (1)

IsPrivate

False (13)

Model Flag

Non Kinetic (4)

Submitter Keywords

Ersilia (3)
FAIR-AIML (3)
Machine Learning Model (3)
FROG (2)
Manuscript Accepted (1)

Classification

bacteria (1294)
viruses (6)
fungi (2)
protozoa (1)

Modification

15.99491 (1)
3x(2)H labeled N6-acetyl-L-lysine (1)
4x(15)N labeled L-arginine (1)
57.02146 (1)
Not available (1)

Study type

Transcription profiling by array (603)
RNA-seq of coding RNA (96)
ChIP-seq (31)
Comparative genomic hybridization by array (21)
Other (19)
DNA-seq (18)
Unknown experiment type (14)
Transcription profiling by tiling array (14)
ChIP-chip by array (13)
RNA-seq of total RNA (11)
High-throughput sequencing (9)
ChIP-chip by tiling array (8)
Methylation profiling by array (8)
RNA-seq of coding RNA from single cells (8)
RNA-seq of non coding RNA (7)
Cell line - High-throughput sequencing (6)
Methylation profiling by high throughput sequencing (4)
Proteomic profiling by array (3)
Cell line - One-color microarray (2)
Transcription profiling by RT-PCR (2)
ATAC-seq (2)
Cell line - Methylation microarray (1)
Two-color microarray (1)
One-color microarray (1)
Human - High-throughput sequencing (1)
Animal - High-throughput sequencing (1)
RNAi profiling by array (1)
Capture-C (1)
MicroRNA profiling by high throughput sequencing (1)
Bisulfite-seq (1)

Release Date

2025 (3118)
2022 (2827)
2023 (2723)
2024 (2518)
2021 (2371)
2020 (1889)
2019 (1490)
2018 (1210)
2017 (903)
2016 (798)
2015 (684)
2014 (567)
2013 (412)
2026 (394)
2012 (351)
2010 (300)
2011 (289)
2009 (195)
2008 (195)
2007 (118)
2005 (73)
2006 (71)
2003 (69)
2004 (52)
2002 (48)
1999 (40)
2001 (38)
2000 (38)
1998 (27)
1997 (1)

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Original data of bacterial antibiotic resistance lipidomics

Plasmid-mediated dissemination of mcr genes has severely compromised colistin efficacy, necessitating adjuvants that restore antibacterial potency without exacerbating toxicity. Despite their essential roles in bacterial survival and virulence, metal ion acquisition systems remain underexplored as t...

2026-08-13 | MTBLS15318 | MetaboLights

Cyromazine accelerates the dissemination of antibiotic resistance genes by promoting the conjugative transfer of the SXT integrative conjugative element

Antimicrobial resistance (AMR) is one of the most urgent challenges in public health, and the horizontal transfer of antibiotic resistance genes (ARGs) mediated by mobile genetic elements (MGEs) drives its widespread global dissemination. Although integrative conjugative elements (ICEs) outnumber...

2025-10-15 | MTBLS13146 | MetaboLights

A synthetic antibiotic class with a deeply-optimized design for overcoming bacterial resistance

The lack of new drugs that are effective against antibiotic-resistant bacteria has caused increasing concern in global public health. Based on this study, we report development of a modified antimicrobial drug through structure-based drug design (SBDD) and modular synthesis. The optimal modified ...

2024-07-03 | MTBLS10516 | MetaboLights

Mechanisms of Iprovalicarb and Cycluron in Promoting Conjugative Transfer of Antibiotic Resistance Genes and Outer Membrane Vesicle-Mediated Dissemination

Detect pesticide residues in water, manure, and soil from waterfowl farms.

2026-08-07 | MTBLS15288 | MetaboLights

Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Klebsiella pneumoniae assays)

The Antibiotic Resistant Sepsis Pathogens Framework Initiative aims to develop a framework dataset of 5 sepsis pathogens (5 strains each) using an integrated application of genomic, transcriptomic, metabolomic and proteomic technologies. The pathogens included in this initiative are: Escheric...

2022-08-03 | MTBLS2322 | MetaboLights

Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Staphylococcus aureus assays)

2022-08-03 | MTBLS1898 | MetaboLights

Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Streptococcus pneumoniae assays)

2022-08-03 | MTBLS2323 | MetaboLights

Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Escherichia coli assays)

2022-08-03 | MTBLS2015 | MetaboLights

Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Streptococcus pyogenes assays)

2022-08-03 | MTBLS2324 | MetaboLights

Macrophage-mediated antibiotic evasion and competitive dominance of mcr-3-carrying Escherichia coli

Mobile colistin resistance (mcr) genes undermine the efficacy of last-line polymyxin antibiotics, and the global prevalence of mcr-3 continues to rise despite reduced colistin use. Here, we show that mcr-3-positive Escherichia coli (E. coli) confers a survival advantage by reprogramming macrophag...

2026-05-30 | MTBLS13550 | MetaboLights

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