Sort   by:  
 Page size 
MetabolomicsBioinspired Rhamnolipid Protects Wheat Against Zymoseptoria tritici Through Mainly Direct Antifungal Activity and Without Major Impact on Leaf Physiology

Rhamnolipids (RLs), glycolipids biosynthesized by the Pseudomonas and Burkholderia genera, are known to display various activities against a wide range of pathogens. Most previous studies on RLs focused on their direct antimicrobial activity, while only a few reports described t...

2022-06-21 | MTBLS4542 | MetaboLights
MetabolomicsBiocontrol potential and antifungal mechanism of three native endophytic Bacillus

Chinese yam tubers are nutrient-rich but highly susceptible to mechanical damage during harvest, which facilitates pathogenic fungal infection at wound sites. This study aimed to identify pathogenic fungi from postharvest yam wounds and screen native endophytic bacteria with antifungal activity f...

2026-10-06 | MTBLS14657 | MetaboLights
TranscriptomicsGene expression response to the antifungal compound sampangine
Sampangine, a plant-derived alkaloid found in the Annonaceae family, exhibits strong inhibitory activity against the opportunistic fungal pathogens Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus. In the present study, transcriptional profiling experiments coupled with the analy...
ORGANISM(S): Candida albicans 
2010-05-26 | E-GEOD-10104 | biostudies-arrayexpress
TranscriptomicsAspergillus fumigatus Af293 response to lactic acid bacteria antifungal activity
The effect of cell free supernatant from the antifungal strain Lactobacillus plantarum 16 on the growth of Aspergillus fumigatus Af293 was assessed. Transcriptome analysis of the genome was performed after ten minutes exposure to antifungal supernatant in order to determine the molecular targets inv...
ORGANISM(S): Aspergillus fumigatus 
2013-08-09 | E-MTAB-1701 | biostudies-arrayexpress
TranscriptomicsGene expression response to the antifungal compound sampangine in C. albicans
Sampangine, a plant-derived alkaloid found in the Annonaceae family, exhibits strong inhibitory activity against the opportunistic fungal pathogens Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus. In the present study, transcriptional profiling experiments coupled with the analy...
ORGANISM(S): Candida albicans 
2010-05-26 | E-GEOD-10075 | biostudies-arrayexpress
TranscriptomicsIdentification and functional characterization of Rca1, a transcription factor involved in both antifungal susceptibility and host response in Candida albicans
The identification of novel transcription factors associated to antifungal response may allow the discovery of fungal specific targets for new therapeutic strategies. A collection of 241 C. albicans transcriptional regulators mutants was screened for altered susceptibility to fluconazole, caspofungi...
ORGANISM(S): Candida albicans 
2012-05-02 | E-GEOD-37682 | biostudies-arrayexpress
no omics definedTranscription profiling of Candida albicans biofilm exposed to amphotericin B, fluconazole or two concentrations of caspofungin
30h of growth biofilms in microfermentors were exposed to caspofungin 0.5 µg/ml, caspofungin 5 µg/ml, fluconazole 80 µg/ml or amphotericin B 8 µg/ml. Control and antifungal-exposed biofilms were recovered at t= 0, 30, 60 and 120 min post exposure to antifungal.
ORGANISM(S): Candida albicans 
2010-03-02 | E-MEXP-2436 | biostudies-arrayexpress
TranscriptomicsResponse of Candida albicans towards a novel antifungal benzimidazole derivative
Fungal infections are a serious health problem in the clinic especially in the immunocompromised patient. Disease ranges from widespread superficial vulvovaginal infections to life-threatening systemic candidiasis. Especially for systemic mycoses only a limited arsenal of antimycotica are available,...
ORGANISM(S): Candida albicans 
2011-07-14 | E-GEOD-21622 | biostudies-arrayexpress
ProteomicsProteomics reveals that the antifungal activity of fenbendazole against Cryptococcus neoformans requires protein kinases.
Cryptococcus neoformans is responsible for over 100,000 deaths annually, and the treatment of this fungal disease is expensive and not consistently effective. Unveiling new therapeutic avenues is crucial. Previous studies have suggested that the anthelmintic drug fenbendazole is an affordable and n...
ORGANISM(S): Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii) 
2024-05-21 | PXD047041 | Pride
Cryptococcus neoformans  antifungal activity  fenbendazole  proteomics  protein kinases 
TranscriptomicsApoEdpL-W treatment
We performed a gene expression analysis of C. albicans SC5314 planktonic cells exposed to the antifungal peptide ApoEdpL-W. Exponentially-growing C. albicans SC5314 cells in SD at 30°C medium were exposed to 2.5 µM ApoEdpL-W and samples were collected after 10 and 30 min. for transcript profiling
ORGANISM(S): Candida albicans 
2011-04-01 | E-MEXP-3084 | biostudies-arrayexpress
Sort   by:  
 Page size