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UnknownOrientation of Antigen Display on Self-Assembling Protein Nanoparticles Influences Immunogenicity.
Not available
S-EPMC7911071 | biostudies-literature
ProteomicsPhage display enables machine learning discovery of cancer antigen specific TCRs
T cells targeting epitopes in infectious diseases or cancer play a central role in spontaneous and therapy-induced immune responses. T-cell epitope recognition is mediated by the binding of the T-Cell Receptor (TCR) and TCRs recognizing clinically relevant epitopes are promising for T-cell based the...
ORGANISM(S): Homo sapiens (Human) 
2025-06-20 | PXD058478 | Pride
Hla-a*02:01 Immunopeptidomics Hla peptides 
TranscriptomicsActivity of the Bacillus anthracis 20 kDa protective antigen component
Edema factor of anthrax binds to the protective antigen (PA83) which cleaves to PA63 and PA20. The role of PA20 was examined using highthroughput gene expression analysis of human peripheral blood mononuclear cells (PBMC) exposed to PA20. Keywords: Toxicity determination PBMC obtained from differe...
ORGANISM(S): Homo sapiens 
2008-08-26 | E-GEOD-12533 | biostudies-arrayexpress
TranscriptomicsT-cell intracellular antigen (TIA) proteins deficiency in murine embryonic fibroblasts alters cell cycle progression and induces autophagy
Background: Mice lacking either T-cell intracellular antigen 1 (TIA1) or TIA1-related/like protein (TIAR/TIAL1) show high rates of embryonic lethality, suggesting a relevant role for these proteins during embryonic development. However, intrinsic molecular and cellular consequences of either TIA1 or...
ORGANISM(S): Mus musculus 
2014-11-05 | E-GEOD-43077 | biostudies-arrayexpress
TranscriptomicsB-Cell Gene Signature with Massive Intrahepatic Production of Antibodies to Hepatitis B Core Antigen in HBV-Associated Acute Liver Failure
Hepatitis B virus (HBV)-associated acute liver failure (ALF) is a dramatic clinical syndrome due to a sudden loss of hepatic cells leading to multiorgan failure. The mechanisms whereby HBV induces ALF are unknown. We used gene expression profiling to establish a molecular definition of hepatitis B v...
ORGANISM(S): Homo sapiens 
2010-04-26 | E-GEOD-14668 | biostudies-arrayexpress
GenomicsAntigen-level resolution of commensal-specific B cell responses enabled by phage-display screening and B cell tetramers
Antigen-level resolution of commensal-specific B cell responses enabled by phage-display screening and B cell tetramers
PRJNA1026914 | ENA
GenomicsMurine splenic CD45+ Erythroid cells display a transcriptomic signature of antigen-presenting cells
Murine splenic CD45+ Erythroid cells display a transcriptomic signature of antigen-presenting cells
PRJNA1378860 | ENA
UnknownAutotransporter-based antigen display in bacterial ghosts.
Not available
S-EPMC4277592 | biostudies-literature
GenomicsHuman coronary plaque T cells are clonally expanded and display cross-reacting viral/self-antigen specificities
Human coronary plaque T cells are clonally expanded and display cross-reacting viral/self-antigen specificities
PRJNA807924 | ENA
UnknownEnhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds.
Not available
S-EPMC9413718 | biostudies-literature
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