Antigen-presenting cells

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Publication Date

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2012 (83)
2015 (80)
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2017 (39)
2008 (36)
2019 (33)
2018 (28)
2009 (27)
2007 (22)
2006 (10)
2005 (10)
2004 (3)

UNIPROT ID/AC

P60568 (1)

CHEBI ID

CHEBI:59132 (3)
CHEBI:15676 (2)
CHEBI:16449 (2)
CHEBI:167922 (1)
CHEBI:32664 (1)
CHEBI:17536 (1)
CHEBI:18186 (1)
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CHEBI:25094 (1)
CHEBI:32816 (1)
CHEBI:78320 (1)
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CHEBI:16335 (1)
CHEBI:16199 (1)
CHEBI:16919 (1)
CHEBI:30769 (1)
CHEBI:20067 (1)

Metabolite Name

Lysine (2)
Glucose (2)
VaL-Gly (1)
Tiglyl carnitine C5:1 (1)
Taurodeoxycholic acid isomer (1)
Stearoylcarnitine isomer (1)
Sn-glycero-3-phospho-1-Inositol (1)
Ser Thr Glu isomer (1)
Sedoheptoluse-7-phosphate (1)
Saringosterol isomer (1)
Ribothymidine isomer (1)
Ribose-5-phosphate (1)
PS(22:1/20:4) (1)
PS(20:5/20:0) (1)
PS(20:1/18:2) (1)
Propionyl carnitine C3 (1)
PI(20:4/18:0) (1)
PG(22:6/17:1) (1)
PG(22:6/16:1) (1)
PG(22:2/16:1) (1)
PG(20:4/18:2) (1)
PG(20:4/18:1) (1)
PG(20:4/18:0) (1)
PG(20:4/16:1) (1)
PG(18:2/22:6) (1)
PG(18:1/22:6) (1)
PG(18:1/22:5) (1)
PG(16:1/20:5) (1)
PG(16:1/16:0) (1)
PG (22:6/18:3) (1)

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2026 (132)
2025 (132)
2024 (108)
2014 (91)
2023 (88)
2022 (63)
2020 (53)
2021 (47)
2019 (27)
2015 (20)
2018 (19)
2017 (19)
2016 (13)
2013 (3)

Modelling Approach

Ordinary differential equation model (5)
Agent-based model (1)

Study status

Completed (2)
Withdrawn (1)

Lab affiliation

Cellular Proteomics, Helmholtz Centre for Infection Research, Braunschweig, Germany (4)
Center of experimental therapeutics Department of oncology UNIL CHUV Ludwig Institute for Cancer Research Lausanne Centre de recherche Agora Rue du Bugnon 25A CH-1005 Lausanne (2)
Department of Molecular Pathology and Biology, Faculty of Military Health Sciences, University of Defence, Trebesska 1575, 500 01 Hradec Kralove, Czech Republic (2)
Division of Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden (2)
Faculty of Chemistry and Center for Synthetic Microbiology (SYNMIKRO) Head of the Core-Facility for Mass Spectrometry Marburg University Hans-Meerwein-Str. 4 35032 Marburg GERMANY (2)
Indian Institute of Science Bengaluru (2)
Infectious Diseases and Immunity in Global Health Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada (2)
University of Oxford (2)
University of Oxford University of Dundee (2)
1 Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands 2 Netherlands Proteomics Centre, Padualaan 8, 3584 CH Utrecht, The Netherlands (1)
1 Department of Immunology, Interfaculty Institute for Cell Biology, Tübingen, Germany 2 German Cancer Consortium (DKTK), DKFZ Partner Site Tübingen, Tübingen, Germany (1)
1Research Unit Protein Science and Metabolomics and Proteomics Core, Helmholtz Zentrum München, German Research Center for Environmental Health, D-85764 Neuherberg, Germany (1)
Army Medical University (Third Military Medical University) (1)
Biochemistry and Pharmacology, MDHS Associate Dean of Graduate Research Bio21 Institute The University of Melbourne, Victoria 3010 Australia (1)
Biotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen (1)
BriaCell Therapeutics Corporation, Berkeley, CA, USA (1)
Centre d'Infection et d'Immunité de Lille Univ. Lille (CIIL), Univ. Lille, CNRS UMR 8204, Inserm U1019, CHU Lille, Institut Pasteur de Lille, F-59000 Lille, France. (1)
Dep. of Oncology-Pathology, Karolinska Institutet, Scilifelab, Stockholm, Sweden (1)
Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC 3010, Australia. Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, VIC 3010, Australia (1)
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Department of Immunotechnology, Lund University, Sweden (1)
Department of Medicinal Chemistry, University of Michigan (1)
Department of Molecular Biology, Faculty of Science, Oncode Institute, Radboud University Nijmegen, 6525 GA Nijmegen, The Netherlands Division of Molecular Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands (1)
Department of Molecular Biology, Princeton University (1)
Department of Neurology, University of North Carolina, Chapel Hill, NC, USA (1)
Department of Ophthalmology, University Medical Center Utrecht, University of Utrecht, Utrecht, Netherlands. Center for Translational Immunology, University Medical Center Utrecht, University of Utrecht, Utrecht, Netherlands. (1)
Department of Pathology and Immunology Washington University School of Medicine St. Louis, MO 63110 (1)
Department of Pathology, Dalhousie University (1)
Dept of Immunology and Oncology, Centro Nacional de Biotecnología (CNB-CSIC), Darwin 3, Campus UAM Cantoblanco, 28079 Madrid, Spain (1)
Dept. Oncology-Pathology, Scilifelab, Karolinska Institutet, Sweden (1)

Keyword

Dendritic cells (1)
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Immunotherapy (1)
Metastatic colorectal cancer (1)

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Submitter Keywords

Immuno-oncology (2)

Classification

fungi (1)

Study type

Transcription profiling by array (410)
ChIP-chip by tiling array (270)
RNA-seq of coding RNA (99)
ChIP-seq (74)
RNA-seq of coding RNA from single cells (70)
DNA-seq (10)
Unknown experiment type (8)
Comparative genomic hybridization by array (8)
RNA-seq of non coding RNA (8)
Other (7)
Human - High-throughput sequencing (6)
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Methylation profiling by high throughput sequencing (5)
RNA-seq of total RNA (5)
Genotyping by array (4)
MicroRNA profiling by array (4)
Animal - High-throughput sequencing (3)
ChIP-chip by array (3)
Transcription profiling by RT-PCR (3)
ATAC-seq (3)
Baseline (2)
Differential (2)
Animal - Single-cell sequencing (2)
ScATAC-seq (2)
Animal - One-color microarray (1)
High-throughput sequencing (1)
Spatial transcriptomics by high-throughput sequencing (1)
Single nucleus RNA sequencing (1)
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Proteomic profiling by array (1)

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2007 (71)
2006 (40)
2005 (31)
2004 (16)
2002 (9)
2000 (7)
2003 (6)
2001 (6)
1997 (3)
1998 (2)
1999 (1)

Location

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United States (1)

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Metabolite assay of T cells that are antigen-specially activated by viscoelastic synthetic antigen presenting cells

Adoptive T cell receptor (TCR)–based immunotherapy offers a powerful strategy to target solid tumors. However, the physical properties of the antigen-presenting interface regulate T cell metabolic programming remains poorly defined. Here we develop synthetic viscoelastic activating cells (SynVAC)...

2026-09-03 | MTBLS15444 | MetaboLights

T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells

Lists of proteins that were commonly detected in total, membrane, TMP, and vesicles.

ORGANISM(S): Mus Musculus (ncbitaxon:10090)

2018-08-15 | MSV000082822 | MassIVE

Analysis of Mouse Dendritic and Antigen presenting cell and Mouse autoimmune and Inflammatory Response

Antigen presenting cells (APC) express receptors recognizing microbes and regulating immune responses by binding to corresponding ligands on immune cells. Having discovered a novel inhibitory pathway triggered by ligation of DC-HIL on APC to a heparin/heparan sulfate-like saccharide of syndecan-4 o...

ORGANISM(S): Mus musculus

2010-05-06 | E-GEOD-17699 | biostudies-arrayexpress

CCL2/CCR2-dependent recruitment of functional antigen-presenting cells into tumors post-chemotherapy

Analysis of MCA205 tumors developed in C57bl/6 mice on day 2, 7 and 10 after intratumoral treatment with doxorubicin (DX) or PBS solvent. DX triggers the immunogenicity of dying tumor cell and activates anti-tumor immunity. Results provided insight into molecular basis of DX induced immune response....

ORGANISM(S): Mus musculus

2014-02-04 | E-GEOD-46275 | biostudies-arrayexpress

Pharmacological Targeting of ALDH1a2 in Dendritic Cells Enhances Antigen Presentation, T Cell Activation and Anti-tumor immunity

Dendritic cell (DC) vaccines have been proposed as cancer immunotherapies due to their role as crucial antigen-presenting cells that regulate T cell functions. Despite considerable efforts to optimize ex vivo priming of DCs, DC vaccines have rarely been successful, suggesting the presence of unknown...

2025-11-03 | MTBLS10389 | MetaboLights

ChIP-chip from KG-1 cells with HIV Tat

HIV-1 Tat can modulate the expression of both HIV and cellular genes. In antigen-presenting cells Tat induces the expression of a subset of interferon-stimulated genes (ISGs) in the absence of interferons (IFNs). We investigated the genome-wide Tat association with cellular promoters in immature den...

ORGANISM(S): Homo sapiens

2013-05-31 | E-GEOD-42191 | biostudies-arrayexpress

The role of antigen presenting cells in the induction of HIV-1 latency in resting CD4+ T-cells

BACKGROUND: Combination antiretroviral therapy (cART) is able to control HIV-1 viral replication, however long-lived latent infection in resting memory CD4+ T-cells persist. The mechanisms for establishment and maintenance of latent infection in resting memory CD4+ T-cells remain unclear. Previously...

ORGANISM(S): Homo sapiens

2015-12-23 | E-GEOD-70106 | biostudies-arrayexpress

Glycogene expression during maturation of human antigen-presenting cells

Dr. van Kooyk's laboratory is exploring the function of antigen presenting cells, such as dendritic cells (DC), that regulate viral-antigen recognition, DC trafficking and T cell binding--all processes that initiate immunity or tolerance. Essential in this is the recognition of ligands by C-type lec...

ORGANISM(S): Homo sapiens

2011-04-29 | E-GEOD-28946 | biostudies-arrayexpress

MPS vaccination alters long-term gene expression of antigen-presenting cells in lymph nodes

Given the importance of sustained antigen presentation in maintenance of lymph node (LN) immune responses, we hypothesized that vaccine antigen availability and antigen-presenting cell (APC) populations may affect LN expansion. Compared to LNs of mice given the full MPS vaccine, LNs of mice given an...

ORGANISM(S): Mus musculus

2024-04-05 | E-MTAB-13698 | biostudies-arrayexpress

Proteomic phenotyping of stimulated Müller cells uncovers profound pro-inflammatory signaling and antigen-presenting capacity

Müller cells are the main macroglial cells of the retina exerting a wealth of functions to maintain retinal homoeostasis. Upon pathological changes in the retina, they become gliotic with both protective and detrimental consequences. Accumulating data also provide evidence for a pivotal role of Müll...

ORGANISM(S): Homo sapiens (Human) Sus scrofa domesticus (domestic pig)

2022-02-16 | PXD028390 | Pride

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