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Genome sequencing of Mycobacterium tuberculosis complex members has accelerated the search for new disease control tools. Antigen mining is one area that has benefited enormously from access to genome data. Here genes that were identified by transcriptome analysis as upregulated in response to an in...
ORGANISM(S): Mycobacterium tuberculosis 
LncRNA-directed Antigenicity Loss Suppresses Immunosurveillance
Depleting the NURF chromatin remodeling complex results in enhanced antitumor immunity using mouse tumor models syngenic to two strain backgrounds. Selective depletion of immune cells from tumor-bearing mice discovers that both CD8+ and CD4+ cells are necessary for enhanced antitumor immunity to NUR...
ORGANISM(S): Mus musculus 
2016-04-29 | GSE71864 | GEO
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