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ProteomicsProteomic Profiling of Kidney Organoids in Extended Culture Conditions
We conducted a global proteomics analysis on kidney organoids at three distinct culture time points: day 22, day 33, and day 38. Our objective wasto investigate the impact of extended culture, beyond the standard differentiation endpoint of day 21, on the organoid protein expression profile.
ORGANISM(S): Homo sapiens (Human) 
2025-10-28 | PXD057360 | Pride
Proteomics Kidney organoids Extended culture Renal disease modeling 
TranscriptomicsTranscriptional analysis of the effect of Alprostadil on NPHP1 URECs
Micro-array experiment was performed on URECs (Urine-derived Renal Epithelial Cells) from a patient carrying recessive NPHP1 mutation. URECs were treated either with 0.04% of DMSO or 2µM of Alprostadil for 24h.
ORGANISM(S): Homo sapiens 
2022-04-05 | E-MTAB-11582 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of NPHP1 URECs
Bulk RNAseq of URECs (Urine-derived Renal Epithelial Cells) from controls or patients carrying recessive NPHP1 mutations.
ORGANISM(S): Homo sapiens 
2022-04-04 | E-MTAB-11593 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of Nphp1-/- KO mouse model kidneys in response to Alprostadil treatment
Bulk RNAseq of kidneys from 5 months-old mice invalidated for Nphp1, which is the main gene responsible for Nephronophtisis, after 4 months of treatment with daily intraperitoneal injection of vehicle of Alprostadil (80µg/kg).
ORGANISM(S): Mus musculus 
2022-04-05 | E-MTAB-11595 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of Nphp1-/- KO mouse model kidneys
Bulk RNAseq of kidneys from 5 months-old mice invalidated for Nphp1 which is the main gene responsible for Nephronophtisis, a genetic kidney disease
ORGANISM(S): Mus musculus 
2022-04-04 | E-MTAB-11594 | biostudies-arrayexpress
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