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TranscriptomicsIllumina gene expression beadchips of human ES cell lines
Publication title: Distinct DNA methylation patterns characterize differentiated human embryonic stem cells and developing human fetal liver To investigate the role of DNA methylation during human development, we developed Methyl-seq, a method that assays DNA methylation at more than 90,000 regions...
ORGANISM(S): Homo sapiens 
2011-05-05 | E-GEOD-29070 | biostudies-arrayexpress
GenomicsHigh-throughput sequencing of ES cell lines, ES-derived cells, and fetal and normal livers
Publication title: Distinct DNA methylation patterns characterize differentiated human embryonic stem cells and developing human fetal liver To investigate the role of DNA methylation during human development, we developed Methyl-seq, a method that assays DNA methylation at more than 90,000 regions...
ORGANISM(S): Homo sapiens 
2011-05-05 | E-GEOD-29071 | biostudies-arrayexpress
GenomicsJarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells
We report on mechanism of interaction between PRC2 complex and Jarid2 and their role in pluripotent cells Examination of PRC2 genomic localization by analysis of Jarid2, Ezh2, Suz12 and Jarid1a occupancy
ORGANISM(S): Mus musculus 
2009-12-24 | E-GEOD-18776 | biostudies-arrayexpress
GenomicsREST–Mediated Recruitment of Polycomb Repressor Complexes in Mammalian Cells
Genome-wide analysis of REST and Polycomb binding in Rest-/- and Eed-/- mouse embryonic stem (mES) cells showed that Rest was required for PRC1 recruitment to a subset of Polycomb regulated neuronal genes. Furthermore, we found that PRC1 can be recruited to Rest binding sites independently of CpG is...
ORGANISM(S): Mus musculus 
2013-06-20 | E-GEOD-48122 | biostudies-arrayexpress
TranscriptomicsmiR-25 regulates Wwp2 and Fbxw7 and promotes reprogramming of mouse somatic cells
To reprogram mouse embryonic fibroblasts (MEFs) to induced Pluripotent Stem Cells (iPSCs), we constructed the PiggyBac (PB) transposon carrying the four Yamanaka factor cDNAs controlled by a CAG promoter (PB-CAG-OCKS, Oct4, cMyc, Klf4 and Sox2). As the baseline reprogramming control, we transfected ...
ORGANISM(S): Mus musculus 
2011-10-10 | E-MTAB-409 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of mouse erythroblasts extracted from fetal liver and adult bone marrow of wild type and miR-144 miR-451 knock out animals.
Analysis of gene expression (mRNA profiles) from mouse Erythroblasts. Wild-type samples
are compared against samples where the miR-451/144 miRNA cluster has been knocked out.
Two cell types are analysed, in vitro cultured erythoblasts and ex vivo isolated erythoblasts.
ORGANISM(S): Mus musculus 
2011-04-20 | E-MTAB-277 | biostudies-arrayexpress
UnknownGiant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A.
Not available
S-EPMC8610419 | biostudies-literature
UnknownPathogenic variants for Mendelian and complex traits in exomes of 6,517 European and African Americans: implications for the return of incidental results.
Not available
S-EPMC4129409 | biostudies-literature
UnknownEvidence of a genetic link between endometriosis and ovarian cancer.
Not available
S-EPMC5068352 | biostudies-literature
UnknownQuantifying and addressing the prevalence and bias of study designs in the environmental and social sciences.
Not available
S-EPMC7733498 | biostudies-literature
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