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UnknownPathologic and molecular features correlate with long-term outcome after adjuvant therapy of resected primary GI stromal tumor: the ACOSOG Z9001 trial.
Not available
S-EPMC4026579 | biostudies-literature
TranscriptomicsETV1 knockdown in GIST cell lines
ETV1 is highly expressed in GIST cells and required for their survival and growth. To identify genes and pathways regulated by ETV1 in GIST, we performed expression profiles of GIST cells after ETV1 knockdown. Two GIST cell lines (GIST48 and GIST882) were infected in duplicate with three shRNA virus...
ORGANISM(S): Homo sapiens 
2010-10-13 | E-GEOD-19396 | biostudies-arrayexpress
UnknownWhole Exome Sequencing Identifies Somatic Variants in an Oral Composite Hemangioendothelioma Characterized by YAP1-MAML2 Fusion.
Not available
S-EPMC9424484 | biostudies-literature
UnknownAlternative driver pathways in peripheral nerve sheath tumors - including DICER1 and/or KRAS alterations.
Not available
S-EPMC12247263 | biostudies-literature
TranscriptomicsImatinib Treatment of GIST882
Gastrointestinal Stromal Tumor frequently harbor mutations in the KIT receptor tyrosine kinase and depend on its activity for growth. This underlies the efficacy of imatinib, a inhibitor of KIT activity, in GIST management. GIST882 is a patient derived GIST cell line that harbor a K640E exon 13 KIT ...
ORGANISM(S): Homo sapiens 
2010-10-13 | E-GEOD-22433 | biostudies-arrayexpress
UnknownNovel Genomic Risk Stratification Model for Primary Gastrointestinal Stromal Tumors (GIST) in the Adjuvant Therapy Era.
Not available
S-EPMC11095631 | biostudies-literature
TranscriptomicsNHGRI_Sarcoma_Baird
Sarcomas are a biologically complex group of tumors of mesenchymal origin. By using gene expression microarray analysis, we aimed to find clues into the cellular differentiation and oncogenic pathways active in these tumors as well as potential biomarkers and therapeutic targets. We examined 181 tum...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-2553 | biostudies-arrayexpress
UnknownBCOR Overexpression Is a Highly Sensitive Marker in Round Cell Sarcomas With BCOR Genetic Abnormalities.
Not available
S-EPMC5106294 | biostudies-literature
TranscriptomicsGastrointestinal stromal tumor GIST: gene expresssion and ChIP analyses
This SuperSeries is composed of the following subset Series: GSE19396: ETV1 knockdown in GIST cell lines GSE22433: Imatinib Treatment of GIST882 GSE22441: Mapping of ETV1 genomic binding sites in gastrointestinal stromal tumor (GIST). Refer to individual Series
ORGANISM(S): Homo sapiens 
2010-10-14 | E-GEOD-22852 | biostudies-arrayexpress
UnknownKIT oncogene inhibition drives intratumoral macrophage M2 polarization.
Not available
S-EPMC3865475 | biostudies-literature
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