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Glioblastoma (GBM) is the most devastating tumour of the brain, endowed with a fatal prognosis. Indeed, the complete eradication of cancer cell disseminated outside the GBM mass still remains a crucial issue. Given the reported strong association existing between Annexin 2A (ANXA2) expression and ce...
ORGANISM(S): Homo sapiens 
RNA-seq analysis of transcriptomes in Wild Type and ANXA2 knockdown HK2 cells
RNA-seq analysis of knockdown of ANXA2 in uterine carcinosarcoma cell line FU-MMT-1 cells.
A novel tsRNA, m7G-3' tiRNA LysTTT, promotes bladder cancer malignancy via regulating ANXA2 phosphorylation
Effect of depletion of ANXA2 and ANXA5 on gene expression in primary murine mesenchymal stromal cells
We conducted this experiment to study the effects of Annexin A2 (ANXA2) on gene expression in human proximal tubular epithelial (HK2) cells in vitro. Short hairpin RNA targeting ANXA2 was designed and cloned into vector pGFP-B-RS for RNAi to generate the recombinant expression plasmids, which were t...
ORGANISM(S): Homo sapiens 
2022-06-16 | GSE159360 | GEO
Uterine carcinosarcomas (UCS) are rare highly aggressive gynecological malignancy. ANXA2 is a calcium-dependent phospholipid binding protein that is over-expressed in various cancers, and plays a pivotal role in tumor migration, metastasis. However, the exact function and mechanism of ANXA2 in UCS h...
ORGANISM(S): Homo sapiens 
2024-08-01 | GSE241829 | GEO
Emerging evidence indicates that tRNA-derived small RNAs (tsRNAs) with the most abundant RNA modifications play an important role in many complex physiological and pathological processes. However, the biological function and regulation mechanism of modified tsRNA in cancer are still poorly understoo...
ORGANISM(S): Homo sapiens 
2024-05-11 | GSE232579 | GEO
To investigate the effects of ANXA2 or ANXA5 depletion on gene expression in primary mesenchymal stromal cells we compared the gene expression profile of sorted mesenchymal stromal cells from the bone marrow of normal wildtype, ANXA2 knockout or ANXA5 knockout mice.
ORGANISM(S): Mus musculus 
2022-06-14 | GSE205762 | GEO
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