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TranscriptomicsHuman bone marrow-derived mononuclear cells (BMMC): rheumatoid arthritis vs. osteoarthritis
Gene expression profiling of BMMC from patients with rheumatoid arthritis (RA) vs. osteoarthritis (OA). Bone marrow was obtained from patients with RA (n=9) or OA (n=10). The bone marrow samples from the 10 OA patients are used as controls.
ORGANISM(S): Homo sapiens 
2011-05-31 | E-GEOD-27390 | biostudies-arrayexpress
TranscriptomicsInteractions of cytokines in peripheral blood cells from Systemic Lupus Erythematosus
SLE patients are always with various disease manifestation. Various cytokines are pointed interacting and playing pathological roles in SLE although the etiopathology is still obscure. In this study, we aimed to investigate the effects of cytokine interactions in the immune response of SLE patients....
ORGANISM(S): Homo sapiens 
2009-05-31 | E-GEOD-12374 | biostudies-arrayexpress
TranscriptomicsJuvenile idiopathic arthritis: peripheral blood cells
Systemic-onset juvenile idiopathic arthritis (soJIA) is a rheumatic disease in childhood characterized by systemic symptoms and a relatively poor prognosis. The peripheral leukocytes are thought to play the pathological role of soJIA although the exact cause is still obscure. In this study, we aimed...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-8361 | biostudies-arrayexpress
TranscriptomicsHuman peripheral blood cells (PB): Effect of Tocilizumab/MRA compared to methotrexate(MTX) treatments on rheumatoid arthritis(RA) patients.
This microarray study was conducted along with SATORI study, the clinical trial evaluated 125 patients with active RA with an inadequate response to low dose of MTX. Patients were allocated to receive either Tocilizumab(TCZ) 8 mg/kg every 4 weeks (TCZ group) or MTX 8 mg/week (MTX/control group) for ...
ORGANISM(S): Homo sapiens 
2014-01-29 | E-GEOD-35455 | biostudies-arrayexpress
TranscriptomicsHuman peripheral blood cells: systemic lupus erythematosus vs healthy individual.
Gene expression profiling of peripheral blood cells from patients with systemic lupus erythematosus (SLE) vs healthy individual (HI). Peripheral blood was obtained from patients with SLE (n=21) and HI (n=45). Blood samples from 45 HI are used as control.
ORGANISM(S): Homo sapiens 
2010-10-01 | E-GEOD-20864 | biostudies-arrayexpress
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