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MetabolomicsAttenuate host susceptibility to respiratory virus invasion by inhibiting interactions between host proteins SLC16A3 and AP1G1

Modulating cell endocytosis activity to reduce host susceptibility to virus represents a promising strategy for antiviral drug development. In this study, we reveal that lactate transporter SLC16A3 as a critical host factor for reducing diverse virus invasion. By performing metabolomics, proteomi...

2025-07-28 | MTBLS12788 | MetaboLights
TranscriptomicsTranscription profiling of Arabidopsis ap3-3 null mutants to identify putative targets of AP3/PI
To identify genes regulated by AP3/PI, we carried out microarray experiments using an Arabidopsis whole genome GeneChip array (ATH1 GeneChip, Affymetrix, Santa Clara, CA) in conjunction with an inducible AP3-GR system. For these experiments, we used 35S::AP3-GR transgenic plants in a 35S::PI, ap3-3 ...
ORGANISM(S): Arabidopsis thaliana 
2008-06-16 | E-GEOD-9702 | biostudies-arrayexpress
UnknownStructural basis of the intracellular sorting of the SNARE VAMP7 by the AP3 adaptor complex.
Not available
S-EPMC3549491 | biostudies-literature
TranscriptomicsH2AZ extended acidic patch is necessary for formation specialized chromatin states in ESCs [RNA-Seq]
The H2A variant H2AZ is essential for embryonic development and for proper execution of developmental gene expression programs in embryonic stem cells (ESCs). Divergent regions in H2AZ are likely key for its functional specialization, but we know little about how these differences contribute to chro...
ORGANISM(S): Mus musculus 
2013-09-23 | E-GEOD-40064 | biostudies-arrayexpress
GenomicsH2AZ extended acidic patch is necessary for formation specialized chromatin states in ESCs [ChIP-Seq]
The H2A variant H2AZ is essential for embryonic development and for proper execution of developmental gene expression programs in embryonic stem cells (ESCs). Divergent regions in H2AZ are likely key for its functional specialization, but we know little about how these differences contribute to chro...
ORGANISM(S): Mus musculus 
2013-09-23 | E-GEOD-40063 | biostudies-arrayexpress
GenomicsH2AZ extended acidic patch is necessary for formation specialized chromatin states in ESCs
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-09-23 | E-GEOD-40065 | biostudies-arrayexpress
GenomicsThe F-box cofactor UFO redirects the LEAFY floral regulator to novel cis-elements
In angiosperms, flower patterning requires the localized expression of the APETALA3 (AP3) floral homeotic gene involved in petal and stamen development. AP3 is synergistically induced by the master transcription factor LEAFY (LFY) and the F-box protein UNUSUAL FLORAL ORGANS (UFO), but the molecular ...
ORGANISM(S): Arabidopsis thaliana 
2023-01-01 | GSE204793 | GEO
UnknownA minimal anaphase promoting complex/cyclosome (APC/C) in Trypanosoma brucei.
Not available
S-EPMC3606461 | biostudies-literature
UnknownZINC FINGER PROTEIN 1 and 8 interact with polycomb repressive complex 2 to repress class B and C floral organ identity genes.
Not available
S-EPMC12828230 | biostudies-literature
UnknownSorting of a multi-subunit ubiquitin ligase complex in the endolysosome system.
Not available
S-EPMC5811209 | biostudies-literature
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