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TranscriptomicsDietary folate depletion and repletion in C57BL/6J mice, ApoE knockout mice, and choline supplemented C57BL/6J mice
Defects in homocysteine and folate metabolism are associated with increased risks for neural tube and congenital heart defects, cardiovascular disease and stroke, cancers, and neurodegeneration. In many but not all cases, dietary supplementation with folate significantly reduces the severity and in...
ORGANISM(S): Mus musculus 
2008-08-27 | E-GEOD-9243 | biostudies-arrayexpress
TranscriptomicsGene expression profiling in thoracic aortas of 8 week and 16 week ApoE knockout mice on a western type diet
Identification of novel pathways in the development of atherosclerosis. Here, we are looking at changes in gene expression that occur in the aorta with the development of atherosclerosis Analysis used RNA from thoracic aortas from chow fed ApoE knockout mice as control samples for comparison to the ...
ORGANISM(S): Mus musculus 
2015-02-03 | E-GEOD-65494 | biostudies-arrayexpress
MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Mice lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-04 | MTBLS8865 | MetaboLights
TranscriptomicsExpression data from the aortas of ApoE knockout, ApoE/Caspase-1 double knockout, and wild-type mice
Caspase-1 activation senses metabolic danger-associated molecular patterns and mediates the initiation of inflammation. Here, we reported that caspase-1 contributes to hyperlipidemia-induced modulation of vascular cell gene expression during early atherosclerosis in vivo. Our results demonstrate the...
ORGANISM(S): Mus musculus 
2015-08-21 | E-GEOD-72248 | biostudies-arrayexpress
GenomicsTranscriptome profiling of murine aortic Vascular Smooth Muscle cells from ApoE knockout and ApoE/Neil3 double knockout mice
Transcriptome profiling of murine aortic Vascular Smooth Muscle cells from ApoE knockout and ApoE/Neil3 double knockout mice
PRJNA590975 | ENA
TranscriptomicsDietary folate depletion and repletion
This SuperSeries is composed of the following subset Series: GSE9242: Dietary folate depletion and repletion in A/J and C57BL/6J mice GSE9243: Dietary folate depletion and repletion in C57BL/6J mice, ApoE knockout mice, and choline supplemented C57BL/6J mice Keywords: SuperSeries Refer to individual...
ORGANISM(S): Mus musculus 
2010-06-20 | E-GEOD-9245 | biostudies-arrayexpress
ProteomicsApoE-knockout mice liver on high fat diet treated with trehalose or agmatine.
ApoE-knockout mice liver on high fat diet developing liver steatosis were treated with trehalose or agmatine for 16 weeks.
ORGANISM(S): Mus musculus (Mouse) 
2024-08-10 | PXD049421 | Pride
Mouse Swath Liver Trehalowe 
GenomicsSex differences in statin response in hypercholesterolemic (Apoe knockout) Four Core Genotypes mice.
Sex differences in statin response in hypercholesterolemic (Apoe knockout) Four Core Genotypes mice.
PRJNA837912 | ENA
GenomicsNPRC deletion mitigated atherosclerosis by inhibiting oxidative stress, inflammation and apoptosis in ApoE knockout mice
NPRC deletion mitigated atherosclerosis by inhibiting oxidative stress, inflammation and apoptosis in ApoE knockout mice
PRJNA976245 | ENA
ProteomicsMouse liver LC-MS/MS - The influence of AICAR - direct activator of AMP-activated protein kinase (AMPK) - on liver proteome in apoE-knockout mice
Shotgun LC-MS/MS on mitochondrial and cytosolic fraction of the liver of apoE-knockout mice
ORGANISM(S): Mus musculus (Mouse) 
2017-05-02 | PXD002615 | Pride
Mouse Hcd Liver Itraq Lc-ms/ms 
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