Sort   by:  
 Page size 
ProteomicsNS7a of SADS-CoV promotes viral infection via inducing apoptosis to suppress Type III interferon production
SADS-CoV is a newly discovered swine coronavirus with potential cross-species transmission risk. Although SADS-CoV-induced host cell apoptosis and attenuated innate immunity has been established, the relation between apoptosis and innate immunity remain obscure. Here, we demonstrate that infection o...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2025-05-06 | PXD047032 | Pride
Viral replication Swine acute diarrhea syndrome virus (sads-cov) Ns7a Apoptosis Apoptosis inducing factor mitochondria associated 1 (aifm1) Ifn-λ 
UnknownCowchock syndrome is associated with a mutation in apoptosis-inducing factor.
Not available
S-EPMC3516602 | biostudies-literature
UnknownSevere multisystem pathology, metabolic acidosis, mitochondrial dysfunction, and early death associated with an X-linked AIFM1 variant.
Not available
S-EPMC8208043 | biostudies-literature
UnknownAIFM1, negatively regulated by miR-145-5p, aggravates hypoxia-induced cardiomyocyte injury.
Not available
S-EPMC9795367 | biostudies-literature
UnknownA novel missense mutation in AIFM1 results in axonal polyneuropathy and misassembly of OXPHOS complexes.
Not available
S-EPMC5693754 | biostudies-literature
TranscriptomicsNotch/HES1-mediated PARP1 activation: A cell-type specific mechanism for tumor suppression
Notch signaling plays both oncogenic and tumor suppressor roles, depending on cell type. In contrast to T cell acute lymphoblastic leukemia (T-ALL), where Notch activation promotes leukemogenesis, induction of Notch signaling in B-ALL leads to growth arrest and apoptosis. The Notch target Hairy/Enha...
ORGANISM(S): Homo sapiens 
2011-12-12 | E-GEOD-26366 | biostudies-arrayexpress
UnknownNS7a of SADS-CoV promotes viral infection via inducing apoptosis to suppress type III interferon production.
Not available
S-EPMC11092342 | biostudies-literature
UnknownThe mitochondrial protease LONP1 maintains oocyte development and survival by suppressing nuclear translocation of AIFM1 in mammals.
Not available
S-EPMC8733232 | biostudies-literature
UnknownEndonuclease G takes part in AIF-mediated caspase-independent apoptosis in Mycobacterium bovis-infected bovine macrophages.
Not available
S-EPMC6052627 | biostudies-literature
UnknownTargeting oxeiptosis-mediated tumor suppression: a novel approach to treat colorectal cancers by sanguinarine.
Not available
S-EPMC10011521 | biostudies-literature
Sort   by:  
 Page size