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Unknown
(5)
Proteomics
(1)
Organisms
Homo sapiens
(1)
Repository
pride
(1)
Technology Type
Mass Spectrometry
(1)
Shotgun proteomics
(1)
Publication Date
2019
(1)
Release Date
2026
(1)
2021
(1)
2019
(1)
2015
(1)
2025
(1)
Lab affiliation
Professor, Department of Biological Sciences, National University of Singapore
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Structural insights into a HECT-type E3 ligase AREL1
Structural insights into a HECT-type E3 ligase AREL1 and its ubiquitination activities in vitro
ORGANISM(S):
Homo sapiens (Human)
2019-11-25
|
PXD016016
|
Pride
Second mitochondria-derived activator of caspase (smac)
Cancer
Hect domain
Apoptosis-resistant e3 ligase 1 (arel1)
Structural biology
Autopolyubiquitination
Ubiquitination
Protein degradation
Apoptosis
Posttranslational modification
Cite
AREL1 E3 ubiquitin ligase inhibits TNF-induced necroptosis via the ubiquitination of MTX2.
Not available
S-EPMC8422393
|
biostudies-literature
Cite
Structural insights into a HECT-type E3 ligase AREL1 and its ubiquitination activities
in vitro
.
Not available
S-EPMC6937569
|
biostudies-literature
Cite
E3 ligase AREL1 controls perinuclear localization of lysosomes and supports Purkinje cell survival.
Not available
S-EPMC12864862
|
biostudies-literature
Cite
E3 ligase AREL1 controls perinuclear localization of lysosomes and supports Purkinje cell survival
Not available
S-SCDT-10_1038-S44318-025-00654-3
|
biostudies-other
Cite
Assembly and structure of Lys33-linked polyubiquitin reveals distinct conformations.
Not available
S-EPMC4390085
|
biostudies-literature
Cite
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