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The 4 Fra2-targeting siRNA and 4 control-siRNA samples were used for analysis. Experiment Overall Design: A microarray procedure was performed according to the Affymetrix protocols (Santa Clara, CA). In brief, total RNA extracted from the tumor samples was analyzed with the Agilent 2100 Bioanalyze...
ORGANISM(S): Homo sapiens 
Previously, we have shown that an AP-1 family member Fra-2, which is hardly expressed in normal mature T cells, is consistently over-expressed in adult T-cell leukemia/lymphoma (ATLL), and together with JunD, upregulates CCR4 and many other genes including proto-oncogenes c-Myb, MDM2, Bcl-6, and SOX...
ORGANISM(S): Homo sapiens 
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