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TranscriptomicsBlood Leukocyte Microarrays to Diagnose Systemic Onset Juvenile Idiopathic Arthritis and Follow IL-1 blocade
Systemic onset Juvenile Idiopathic Arthritis (SoJIA) represents up to 20% of Juvenile Idiopathic Arthritis (JIA). We have previously reported that this disease is Interleukin 1 (IL1)-mediated, and that IL-1 blockade results in clinical remission in the majority of patients. The diagnosis of SoJIA, h...
ORGANISM(S): Homo sapiens 
2007-09-01 | E-GEOD-8650 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of whole blood transcriptional response to Respiratory Syncytial Virus, Influenza and Rhinovirus lower respiratory tract infection (LRTI) in children
Analysis of transcriptional profiles in whole blood from children < 2 years of age (and healthy matched controls) with RSV, rhinovirus and influenza infection. The hypothesis tested is that transcriptional profile heterogeneity will reflect patient clinical heterogeneity and that RSV infection induc...
ORGANISM(S): Homo sapiens 
2013-11-12 | E-GEOD-38900 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human stemic juvenile idiopathic arthritis, , systemic lupus erythematosus,, type I diabetes, metastatic melanoma, acute infections, or liver-transplant recipients undergoing immunosuppressive therapy (n = 37)
The analysis of patient blood transcriptional profiles offers a means to investigate the immunological mechanisms relevant to human diseases on a genome-wide scale. In addition, such studies provide a basis for the discovery of clinically relevant biomarker signatures. We designed a strategy for mic...
ORGANISM(S): Homo sapiens 
2008-10-04 | E-GEOD-11907 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human systemic lupus erythematosus patients to develop a transcriptional indicator of disease progression
Transcriptional modules were used as a basis for the selection of biomarkers and the development of a multivariate transcriptional indicator of disease progression in patients with systemic lupus erythematosus. Experiment Overall Design: The proposed biomarker-selection strategy relies on modules ...
ORGANISM(S): Homo sapiens 
2008-10-01 | E-GEOD-11909 | biostudies-arrayexpress
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
UnknownTiming of surgery following SARS-CoV-2 infection: an international prospective cohort study.
Not available
S-EPMC8206995 | biostudies-literature
UnknownSARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.
Not available
S-EPMC8652887 | biostudies-literature
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