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TranscriptomicsA metabolomics analysis of Salmonella infection
The interplay between pathogens and hosts has been studied for decades using targeted approaches such as the analysis of mutants and host immunological responses. Although much has been learned from such studies, they focus on individual pathways and fail to reveal the global effects of infection on...
ORGANISM(S): Mus musculus 
2011-02-08 | E-GEOD-21720 | biostudies-arrayexpress
TranscriptomicsA metabolomics analysis of gallbladder lipid droplet formation due to Salmonella infection
To cause disease, Salmonella enterica serovar Typhimurium requires two type-III secretion systems, encoded on Salmonella Pathogenicity Islands 1 and 2 (SPI-1 and -2). These secretion systems serve to deliver virulence proteins, termed effectors, into the host cell cytosol. While the importance of th...
ORGANISM(S): Mus musculus 
2011-08-22 | E-GEOD-27604 | biostudies-arrayexpress
TranscriptomicsMetabolomics reveals phospholipids as important nutrient sources during Salmonella growth in bile in vitro and in vivo
During the colonization of hosts, bacterial pathogens are presented with many challenges that must be overcome for colonization to successfully occur. This requires bacterial sensing of the surroundings and adaptation to the conditions encountered. One of the major impediments to pathogen colonizati...
ORGANISM(S): Mus musculus 
2011-07-06 | E-GEOD-30404 | biostudies-arrayexpress
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