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MetabolomicsTargeting arginine metabolism reverses bone immunosuppressive microenvironment and metastasis in ARID1A-deficient triple negative breast cancer

Bone metastasis is a lethal consequence of breast cancer. AT-rich interaction domain 1A gene (ARID1A), a subunit of the switch/sucrose non-fermentable (SWI/SNF) complex, regulates immunosuppressive tumor microenvironment. ARID1A deficient triple negative breast cancer promotes bone metastasis.To ...

2026-03-24 | MTBLS12768 | MetaboLights
ProteomicsAcetylation of ARID proteins by Ralstonia solanacearum effector PopP2 in plants
Like many gram-negative phytopathogenic bacteria, Ralstonia solanacearum uses a type III secretion system to deliver into host cells a cocktail of effector proteins that can interfere with plant defences and promote infection. One of these effectors, the nuclear-targeted PopP2 acetyltransferase, was...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) Nicotiana benthamiana Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum) Escherichia coli 
2025-05-06 | PXD055620 | Pride
Ralstonia solanacearum Acetylation Popp2 Arid proteins Plant Nanolc-ms/ms 
TranscriptomicsARID-DNA interactions are essential for SWI/SNF function
Every known SWI/SNF chromatin-remodeling complex incorporates an ARID DNA binding domain-containing subunit. Despite being a ubiquitous component of these complexes, physiological roles for this domain remain undefined. We screened an N-ethyl-N-nitrosurea (ENU) mutagenized library for ARID domain ...
ORGANISM(S): Mus musculus 
2012-01-15 | E-GEOD-32116 | biostudies-arrayexpress
TranscriptomicsThe disordered extensions of the Arid5a core ARID domain modulate its DNA- and RNA-binding propensities
ARID (AT-rich interacting domain) proteins are a heterogeneous family of DNA-binding proteins involved in transcriptional regulation. No precise DNA-binding preferences have yet been defined for the aberrant member Arid5a. In addition, the protein binds to mRNA motifs for transcript stabilisation, p...
ORGANISM(S): synthetic construct 
2024-03-21 | GSE256029 | GEO
UnknownDNA-binding properties of ARID family proteins.
Not available
S-EPMC546134 | biostudies-literature
UnknownTwo related ARID family proteins are alternative subunits of human SWI/SNF complexes.
Not available
S-EPMC1134073 | biostudies-literature
TranscriptomicsA blueprint for C4 photosynthesis in the rice paddy: insights from the noxious weed Echinochloa glabrescens
The C4 pathway is a highly complex trait that increases photosynthetic efficiency in over sixty plant lineages. Although the majority of C4 plants occupy disturbed, arid and nutrient-poor habitats, some grow in high-nutrient, waterlogged conditions. One such example is Echinochloa glabrescens, which...
ORGANISM(S): Echinochloa glabrescens 
2015-08-11 | E-MTAB-4422 | biostudies-arrayexpress
GenomicsThe disordered extensions of the Arid5a core ARID domain modulate its DNA- and RNA-binding propensities
The disordered extensions of the Arid5a core ARID domain modulate its DNA- and RNA-binding propensities
PRJNA1077695 | ENA
UnknownDiversity and saline-alkali resistance of Coleoptera endosymbiont bacteria in arid and semi-arid climate.
Not available
S-EPMC11302287 | biostudies-literature
UnknownComprehensive analysis and identification of drought-responsive candidate NAC genes in three semi-arid tropics (SAT) legume crops.
Not available
S-EPMC8059324 | biostudies-literature
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