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TranscriptomicsEVALUATION IN A MOUSE PROSTATE CANCER XENOGRAFT MODEL OF THE EFFECTIVENESS OF CYCLOPHOSPHAMIDE METRONOMIC REGIMEN
The aim of this study was to evaluate in a mouse prostate cancer xenograft model the effectiveness of cyclophosphamide metronomic regimen, as single agent or in combination with standard docetaxel therapy. We used a human prostate cancer cell line to establish tumours in mice and we treated the anim...
ORGANISM(S): Homo sapiens 
2012-12-30 | E-GEOD-27930 | biostudies-arrayexpress
TranscriptomicsRecombinant human lactoferrin activates human dendritic cells via Toll-like receptors-2 and -4
Talactoferrin alfa (TLF) is a unique recombinant version of human lactoferrin, an important immunomodulatory protein present in exocrine secretions and in the secondary granules of neutrophils. Talactoferrin has demonstrated anti-cancer activity in preclinical studies and in Phase III clinical tria...
ORGANISM(S): Homo sapiens 
2013-12-30 | E-GEOD-26438 | biostudies-arrayexpress
TranscriptomicsCharacterization of the genetic mouse model of non-small cells lung cancer p53R172HM-bM-^HM-^Fg/KrasG12D
Background: Non-small cell lung cancer (NSCLC) accounts for 81% of all cases of lung cancer and they are often fatal because 60% of the patients are diagnosed at an advanced stage. Besides the need for earlier diagnosis, there is a great need for additional effective therapies. In this work we inves...
ORGANISM(S): Mus musculus 
2013-09-25 | E-GEOD-51144 | biostudies-arrayexpress
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