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TranscriptomicsTranscriptional profiling of ATCC46645 strain and isogenic M-NM-^TpacC Aspergillus fumigatus mutant during murine infection
In lung diseases caused by the major mould pathogen Aspergillus fumigatus the pulmonary epithelium is destroyed by invasive growth of fungal hyphae, a process thought to require fungal proteases. Here we show that the A. fumigatus pH-responsive transcription factor PacC governs expression of secrete...
ORGANISM(S): Aspergillus fumigatus 
2014-10-20 | E-GEOD-54810 | biostudies-arrayexpress
ProteomicsAllogeneic antibodies specifically target AML antigen NuSAP1 after bone marrow transplantation
Identifying the targets of immune response after allogeneic hematopoietic cell transplantation (HCT) promises to provide relevant immune therapy candidate proteins. We used protein microarrays to serologically identify Nucleolar and Spindle Associated Protein 1 (NuSAP1) and Chromatin Assembly Factor...
ORGANISM(S): Homo sapiens 
2010-06-21 | E-GEOD-15255 | biostudies-arrayexpress
TranscriptomicsMethylation profiling of Low-Risk Myelodysplastic Syndromes (MDSs)
Genome-wide expression and methylation profiling identifies novel targets with aberrant hypermethylation and reduced expression in low-risk myelodysplastic syndromes (MDSs). Gene expression profiling signatures may be used to classify the subtypes of Myelodysplastic syndrome (MDS) patients. However,...
ORGANISM(S): Homo sapiens 
2012-09-28 | E-GEOD-41215 | biostudies-arrayexpress
UnknownCorrelation between 25-hydroxyvitamin D/D3 Deficiency and COVID-19 Disease Severity in Adults from Northern Colorado.
Not available
S-EPMC9782165 | biostudies-literature
TranscriptomicsCommon and overlapping oncogenic pathways contribute to the evolution of acute myeloid leukemias.
In this report we demonstrate that the ability to alter self-renewal in vitro and in vivo is a more generalized property of leukemia-associated oncogenes. We further demonstrate that disparate leukemia-associated oncogenes initiate early common and overlapping transformation and self-renewal gene ex...
ORGANISM(S): Homo sapiens 
2011-06-27 | E-GEOD-23143 | biostudies-arrayexpress
UnknownThe effect of missing data and imputation on the detection of bias in cognitive testing using differential item functioning methods.
Not available
S-EPMC8961895 | biostudies-literature
UnknownLong-Term Safety and Clinical Outcomes With Olipudase Alfa Enzyme Replacement Therapy in Children and Adolescents With Acid Sphingomyelinase Deficiency.
Not available
S-EPMC12426810 | biostudies-literature
UnknownOlipudase alfa enzyme replacement therapy for acid sphingomyelinase deficiency (ASMD): sustained improvements in clinical outcomes after 6.5 years of treatment in adults.
Not available
S-EPMC10131350 | biostudies-literature
UnknownAvoiding weight gain in cardiometabolic disease: a systematic review.
Not available
S-EPMC4291140 | biostudies-literature
TranscriptomicsA Key Role for Chd1 in Histone H3 Dynamics at the 3' Ends of Long Genes in Yeast (H3K4me3 or H3K36me3 to input)
Chd proteins are ATP-dependent chromatin remodeling enzymes implicated in biological functions from transcriptional elongation to control of pluripotency. Here, we examine roles of Chd1 in replication- independent dynamics of histone H3 in yeast. Using genome-wide ChIP on chip analysis, we find tha...
ORGANISM(S): Saccharomyces cerevisiae 
2012-06-07 | E-GEOD-38492 | biostudies-arrayexpress
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