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TranscriptomicsTranscription profiling of human hematopoietic stem/progenitor cells treated with TGF-beta1 to idetntify its target genes (reference series)
Leukemias and other cancers possess a rare population of cells capable of self-renewal, and eradication of these cancer stem cells is likely necessary for long-term cancer-free survival. Given that both normal and cancer stem cells are capable of self-renewal the extent to which cancer stem cells re...
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-3725 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse isolated granulocyte macrophage progenitors were incubated with a retrovirus that expressed either GFP or MLL-AF9 and GFP
Leukemias and other cancers possess a rare population of cells capable of self-renewal, and eradication of these cancer stem cells is likely necessary for long-term cancer-free survival. Given that both normal and cancer stem cells are capable of self-renewal the extent to which cancer stem cells re...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-4416 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Aspergillus fumigatus cultures using RNA subjected to 1, 2 or no rounds of amplifciation to identify amplification protocol dependent differences in log ratios of intensity
To assess the credibility of our experimental data in E-TABM-327 we compared transcriptional profiiles of media shifted Aspergillus fumigatus cultures using RNA that was subjected to 1, 2 or no rounds of amplification. The protocol dependent changes in log ratios were assessed
ORGANISM(S): Aspergillus fumigatus 
2008-01-10 | E-TABM-330 | biostudies-arrayexpress
UnknownERCC6L2 mitigates replication stress and promotes centromere stability.
Not available
S-EPMC12003248 | biostudies-literature
UnknownNucleotide oligomerization domain 1 is a dominant pathway for NOS2 induction in vascular smooth muscle cells: comparison with Toll-like receptor 4 responses in macrophages.
Not available
S-EPMC2913099 | biostudies-literature
MetabolomicsCyclooxygenase-2, Asymmetric Dimethylarginine, and the Cardiovascular Hazard From Nonsteroidal Anti-Inflammatory Drugs (Murine and human plasma quantitative L-arginine and methylarginines UPLC-MS/MS assay)

BACKGROUND: Large-scale, placebo-controlled trials established that nonsteroidal anti-inflammatory drugs confer a cardiovascular hazard: this has been attributed to depression of cardioprotective products of cyclooxygenase (COX)-2, especially prostacyclin. An alternative mechanis...

2019-08-22 | MTBLS685 | MetaboLights
UnknownDissemination of Verona Integron-encoded Metallo-β-lactamase among clinical and environmental Enterobacteriaceae isolates in Ontario, Canada.
Not available
S-EPMC7596063 | biostudies-literature
UnknownPerioperative management of renin-angiotensin system inhibitors in patients undergoing elective major noncardiac surgery: a mixed model investigation using systematic review, meta-analysis, multicentre service evaluation, and national survey.
Not available
S-EPMC12674026 | biostudies-literature
UnknownThe biochemical mechanism of Rho GTPase membrane binding, activation and retention in activity patterning
Not available
S-SCDT-10_1038-S44318-025-00418-Z | biostudies-other
GenomicsMolecular Genetic Studies of Developmental Brain Disorders

Study 1
2R01-NS050375 (PI: DOBYNS, William B.)
The genetic basis of mid-hindbrain malformations
Our general goal for this project is to advance our understanding of human developmental disorders that involve the brainstem and cerebellum - brain structures derived from the embryoni...

phs000455.v1.p1 | EGA
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