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ProteomicsEffects of chronic social stress on mitochondrial and mitochondrial-associated membrane protein networks in the mouse brain
Stressors challenge metabolic processes to adapt to ever-changing environmental conditions and herein, the brain is exceptionally amenable to change. Simultaneously, the high cerebral energy demands may render the brain particularly vulnerable to the metabolic consequences of psychological stress. M...
ORGANISM(S): Mus musculus (Mouse) 
2022-10-13 | PXD015983 | Pride
Mitochondrial-associated membrane Brain Mouse Chronic stress 
TranscriptomicsTranscription profiling of rat insulinoma INS-1 cell lines (FLP-In T-REx)
Four rat insulinoma cell lines (INS-1) were generated that contain a FRT site for FLP recombinase mediated site specific integration of specific genes. In addition, the cell lines contain the tetracycline repressor allowing tetracycline (tet) induction of the introduced gene. By comparing the gene e...
ORGANISM(S): Rattus norvegicus 
2008-06-11 | E-GEOD-1591 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Rattus norvegicus pancreatic beta cell line expressing HNF1b, HNF4a2 or HNF6
This SuperSeries is composed of the following subset Series:; GSE1589: Targets of HNF1b, HNF4a2 and HNF6 in INS-1 cells; GSE1590: Targets of HNF1b mutants in INS-1; GSE1591: INS-1 cell lines (FLP-In T-REx) Experiment Overall Design: Refer to individual Series
ORGANISM(S): Rattus norvegicus 
2007-11-29 | E-GEOD-6428 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat insulinoma line INS-1 to identify targets of HNF1b mutants in INS-1
A rat insulinoma cell line (INS-1) was generated that contains a FRT site for FLP recombinase mediated site specific integration of specific genes. In addition, the line contains the tetracycline repressor allowing tetracycline (tet) induction of the introduced gene. By comparing the gene expression...
ORGANISM(S): Rattus norvegicus 
2008-06-11 | E-GEOD-1590 | biostudies-arrayexpress
GenomicsUK10K RARE CHD
In the UK10K project we propose a series of complementary genetic approaches to find new low frequency/rare variants contributing to disease phenotypes. These will be based on obtaining the genome wide sequence of 4000 samples from the TwinsUK and ALSPAC cohorts (at 6x sequence coverage), and the ex...
EGAS00001000125 | EGA
GenomicsEGAS00001000317-sc-20140326 - samples
The exome sequencing is performed using Agilent SureSelect 50Mb exome v3 and Hiseq 75bp paired reads with an mean sequencing coverage target of 50X.
EGAD00001000799 | EGA
Genomicsuk10k_rare_chd_rel_2012_07_05-sc-20120727 - samples
UK10K_RARE_CHD REL-2012-07-05
EGAD00001000210 | EGA
Genomicsuk10k_rare_chd_rel_2012_01_13-sc-20120611 - samples
UK10K_RARE_CHD REL-2012-01-13
EGAD00001000178 | EGA
Genomicsuk10k_rare_chd_rel_2012_02_22-sc-20120613 - samples
UK10K_RARE_CHD REL-2012-02-22
EGAD00001000192 | EGA
Genomicsuk10k_rare_chd_rel_2013_04_20-sc-20130522 - samples
UK10K_RARE_CHD REL-2013-04-20
EGAD00001000413 | EGA
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