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TranscriptomicsQuantitative trait loci (QTL) study identifies novel genomic regions associated to Chiari-Like Malformation in Griffon Bruxellois dogs
Chiari-like malformation (CM) is a developmental abnormality of the craniocervical junction that is common in the Griffon Bruxellois (GB) breed with an estimated prevalence of 65%. This disease is characterized by overcrowding of the neural parenchyma at the craniocervical junction and disturbance o...
ORGANISM(S): Canis lupus familiaris 
2014-05-19 | E-GEOD-52221 | biostudies-arrayexpress
ProteomicsSemi-quantitative proteomics of mammalian cells exposed to non-ionizing electromagnetic fields
Unbiased SILAC-based proteomics of human and mouse cells exposed to non-ionizing electromagnetic fields (EMFs) such as those emitted by power-lines (ELF), mobile cellular systems (UMTS) and wireless networking devices (WiFi).
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2017-02-01 | PXD002862 | Pride
Inverse metabolic labeling Embryonic stem cells Exposure Silac Radio frequency Osteosarcomas Mouse Human Fibroblasts Extremely low frequency Non-ionizing electromagnetic fields 
UnknownA mutation of Ikbkg causes immune deficiency without impairing degradation of IkappaB alpha.
Not available
S-EPMC2840324 | biostudies-literature
TranscriptomicsShear flow vs. static culture of d9 and d12 megakaryocytes
d9 and d12 Mks were either cultured statically or subjected to shear flow for 30 min; at d9, half the Mks were placed back in culture for 30 min (60 min time point) Megakaryocytes (Mks) are exposed to shear flow as they migrate from the bone marrow hematopoietic compartment into circulation thus rel...
ORGANISM(S): Homo sapiens 
2016-02-01 | E-GEOD-75766 | biostudies-arrayexpress
GenomicsHow C/EBPa creates an elite cell state for reprogramming to pluripotency [ChIPseq]
Mouse Bcell, upon ectopic expression of the transcription factor Cebpa for 18h, can be reprogrammed to iPS with extremely high efficiency. To understand the molecular control of this phenomena we performed multiple high throughtput functionnal genomic analysis. Genome binding/occupancy of transcript...
ORGANISM(S): Mus musculus 
2016-02-19 | E-GEOD-71215 | biostudies-arrayexpress
TranscriptomicsHow C/EBPa creates an elite cell state for reprogramming to pluripotency [4C]
Mouse Bcell, upon ectopic expression of the transcription factor Cebpa for 18h, can be reprogrammed to iPS with extremely high efficiency. To understand the molecular control of this phenomena we performed multiple high throughtput functionnal genomic analysis. Circularized chromosome conformation c...
ORGANISM(S): Mus musculus 
2016-02-19 | E-GEOD-75481 | biostudies-arrayexpress
TranscriptomicsHow C/EBPa creates an elite cell state for reprogramming to pluripotency [RNAseq]
Mouse Bcell, upon ectopic expression of the transcription factor Cebpa for 18h, can be reprogrammed to iPS with extremely high efficiency. To understand the molecular control of this phenomena we performed multiple high throughtput functionnal genomic analysis. Transcriptomic by RNAseqencing (polyA+...
ORGANISM(S): Mus musculus 
2016-02-19 | E-GEOD-71217 | biostudies-arrayexpress
TranscriptomicsHow C/EBPa creates an elite cell state for reprogramming to pluripotency [ATACseq]
Mouse Bcell, upon ectopic expression of the transcription factor Cebpa for 18h, can be reprogrammed to iPS with extremely high efficiency. To understand the molecular control of this phenomena we performed multiple high throughtput functionnal genomic analysis. Chromatin accessibility by ATACseq in ...
ORGANISM(S): Mus musculus 
2016-02-19 | E-GEOD-71214 | biostudies-arrayexpress
UnknownMutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders.
Not available
S-EPMC2082049 | biostudies-literature
TranscriptomicsHow C/EBPa creates an elite cell state for reprogramming to pluripotency [array]
Mouse Bcell, upon ectopic expression of the transcription factor Cebpa for 18h, can be reprogrammed to iPS with extremely high efficiency. To understand the molecular control of this phenomena we performed multiple high throughtput functional genomic analysis. Transcriptomic by microarray in Bcell, ...
ORGANISM(S): Mus musculus 
2016-02-19 | E-GEOD-71213 | biostudies-arrayexpress
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