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TranscriptomicsEnhanced CLIP uncovers IMP protein-RNA targets in human pluripotent stem cells important for cell adhesion and survival [eCLIP-Seq]
Human pluripotent stem cells (hPSCs) require precise control of post-transcriptional RNA networks to maintain proliferation and survival. Using a recently developed enhanced UV crosslinking and immunoprecipitation (eCLIP) approach, we identify RNA targets of the IMP/IGF2BP family of RNA-binding prot...
ORGANISM(S): Homo sapiens 
2016-04-07 | E-GEOD-78507 | biostudies-arrayexpress
TranscriptomicsElodea nuttallii transcriptomic response to mercury, monomethyl-mercury, copper and UV-B radiation
The mechanisms of metal accumulation and toxicity in primary producers are not well understood. In a previous study (deposited in ArrayExpress archive under accession E-MTAB-892), we generated a dataset giving a fist insight into transcriptomic response of the aquatic macrophyte Elodea nuttallii to ...
ORGANISM(S): Elodea nuttallii 
2014-06-30 | E-MTAB-2557 | biostudies-arrayexpress
TranscriptomicsGene Regulation of Intestinal Porcine Epithelial Cells IPECM-bM-^@M-^QJ2 is Dependent on the Site of Deoxynivalenol Toxicological Action
Here we analysed different mechanisms of apical and basolateral deoxynivalenol (DON) toxicity reflected in the gene expression. We used the jejunum derived, polarized intestinal porcine epithelial cell line IPECM-bM-^@M-^QJ2 as an in vitro cell culture model. Luminal and blood stream DON intoxicatio...
ORGANISM(S): Sus scrofa 
2012-12-31 | E-GEOD-33246 | biostudies-arrayexpress
TranscriptomicsIntegrative AUF1 PAR-CLIP analysis uncovers AUF1 roles in translation and genome integrity (PAR-CLIP)
We report that AUF1 modulates global mRNA stability and translation, in turn promoting the maintenance of DNA integrity. Please see individual series. In short, for AUF1 PAR-CLIP, the four isoforms of AUF1 (p37, p40, p42, and p45) tagged with a Flag epitope were expressed in HEK293 cells. For total ...
ORGANISM(S): Homo sapiens 
2014-11-05 | E-GEOD-52971 | biostudies-arrayexpress
UnknownMutual learning for joint disease detection and severity prediction reveals multimodal pathogenesis for neurodegenerative disorders.
Not available
S-EPMC12758602 | biostudies-literature
UnknownGlobal hospital-based disease management of acute diverticulitis: a prospective, international cohort study.
Not available
S-EPMC12512976 | biostudies-literature
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