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Overexpression of the transcription factor RHOXF2 in the HEK293_M2 cells confers resistance to several DNA damaging agents. To understand that resistance mechanism, we cultured HEK293_M2 with or without overexpression of RHOXF2 in the presence of 40nM of mitomycin C or DMSO (control) and profiled th...
ORGANISM(S): Homo sapiens 
The human ORFeome collection version 3.1 was stably integrated into HEK293 (lentivirus based). The cells harboring the collection were harvested, collection specific DNA was amplified and sequenced to assess the collection representation.
ORGANISM(S): Homo sapiens 
Identification of human ORFs conferring resistance to various drug treatments when overexpressed into HEK293-M2, assessed by microarrays
ORGANISM(S): Homo sapiens 
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