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ProteomicsEvaluating the Performance of the Astral Mass Analyzer for Quantitative Proteomics Using Data Independent Acquisition
We evaluate the quantitative performance of the newly released Asymmetric Track Lossless (Astral) analyzer. Using data independent acquisition, the Orbitrap Astral mass spectrometer quantifies 5 times more peptides per unit time than state-of-the-art Orbitrap mass spectrometers, which have long been...
ORGANISM(S): Homo Sapiens 
PXD042704 | panorama
ProteomicsNarrow-window DIA: Ultra-fast quantitative analysis of comprehensive proteomes with high sequencing depth. Evaluation of window width and injection time.
Mass spectrometry (MS)-based proteomics aims to characterize comprehensive proteomes in a fast and reproducible manner. Here, we present an ultra-fast scanning data-independent acquisition (DIA) strategy consisting on 2-Th precursor isolation windows, dissolving the differences between data-dependen...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000095977 | MassIVE
TranscriptomicsExpression data from CD-1 mouse liver samples obtained from in-vivo treatment with genotoxic carcinogens, non-genotoxic carcinogens or non-hepatocarcinogens.
Assessing the carcinogenic potential of drug candidates is a costly procedure which requires the life-long treatment of rodents at different dose levels. A promising approach, which may to a certain degree reduce the need for animal studies in the future is toxicogenomics. The idea is to employ micr...
ORGANISM(S): Mus musculus 
2013-09-11 | E-GEOD-44783 | biostudies-arrayexpress
TranscriptomicsIdentification of novel candidate oncogenes in chromosomal region 17p11.2-p12 in human osteosarcoma
in 25% - 30% of all OS cases the chromosome region 17p11.2-p12 is aberrant. Using SNP array in conjunction with expression microarrays we try to identify genes which can be classified as oncogens or are in someway benificial to the survival of the tumor. To identify minimal significant amplified reg...
ORGANISM(S): Homo sapiens 
2013-04-15 | E-GEOD-32964 | biostudies-arrayexpress
TranscriptomicsIdentification of differentially expressed genes in equine endometrium at day 8 and 12 of pregnancy
In order to systematically analyze the maternal, i.e. the endometrial, changes in the equine endometrium underlying the complex embryo-maternal dialogue during early pregnancy, a transcriptome study of endometrium samples from five mares at day 8 and six mares at day 12 of early pregnancy and the co...
ORGANISM(S): Equus caballus 
2010-06-30 | E-GEOD-21046 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression changes during the estrous cycle in equine endometrium
The equine endometrium exhibits characteristic morphological and functional changes during the estrous cycle controlled by the interplay of progesterone and estradiol. A microarray analysis of endometrial tissue samples derived from 5 time points of the estrous cycle (D0, D3, D8, D12, and D16) was p...
ORGANISM(S): Equus caballus 
2012-10-23 | E-GEOD-39043 | biostudies-arrayexpress
TranscriptomicsArabidopsis tissue atlas
We used state of the art mass spectrometry and RNA sequencing (RNA-Seq) to provide the first integrated proteomic, phosphoproteomic and transcriptomic atlas of Arabidopsis. For this we measured 30 different Arabidopsis tissues from adult plants, seedlings, callus and cell culture samples to an avera...
ORGANISM(S): Arabidopsis thaliana 
2020-01-10 | E-MTAB-7978 | biostudies-arrayexpress
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
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