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TranscriptomicsComparison of gene expression profiles of normal human bronchial epithelial cells in 2D and 3D cultural conditions
The experiment is part of a project to study DNA repair process after ionizing radiation in organotypic 3-dimentional human bronchial epithlial cell culture. Human bronchial epithelial cells were grown in tissue culture flask (2D) or in matrics gel (3D). Three independent cultures were done for eac...
ORGANISM(S): Homo sapiens 
2011-07-26 | E-GEOD-27520 | biostudies-arrayexpress
GenomicsHomo sapiens
RAD51 Interconnects Between DNA Replication, DNA Repair and Immunity
PRJNA375818 | ENA
GenomicsTranscriptional elongation requires DNA break-induced signaling
We have previously shown that RNA polymerase II (Pol II) pause release and transcriptional elongation involve phosphorylation of the factor TRIM28 by the DNA damage response (DDR) kinases ATM and DNA-PK. Here, we report a significant role for DNA breaks and DDR signaling in the mechanisms of transcr...
ORGANISM(S): Homo sapiens 
2015-11-20 | E-GEOD-75170 | biostudies-arrayexpress
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