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TranscriptomicsTranscription profiling of mouse muscle satellite cell-derived myoblasts (MyoD-/-, p53-/-)
Muscle satellite cells are a self-renewing pool of stem cells that give rise to daughter myogenic precursor cells in adult skeletal muscle. Published and preliminary data indicated that MyoD and p53 genes are involved in satellite cell differentiation. We would like to know what downstream genes of ...
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-3244 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse 2C5/7 myoD-/-;myf5-/- fibroblast cells expressing MyoD, Myf5, myogenin, or hrGFP
Gene expression changes induced by MyoD or Myf5 were examined in a double-knockout fibroblast cell line lacking endogenous functional myoD or myf5 genes. Use of this cell line precluded the possibility of auto- or cross-activation of endogenous myoD or myf5. Myogenin or hrGFP were expressed in paral...
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-3245 | biostudies-arrayexpress
TranscriptomicsSkeletal muscle myoblasts: GATA4-Wt, -KO, -OE; day 0, 3
Gene expression in satellite cell-derived primary myoblasts islolated from Gata4-loxP mice. Myoblasts were infected with nLacZ for control (Wt), Cre recombinase to knockout GATA4 (KO), or GATA4 expression vector to overexpress GATA4 (OE). Infected myoblasts were cultured in growth medium (day 0) the...
ORGANISM(S): Mus musculus 
2015-02-18 | E-GEOD-66016 | biostudies-arrayexpress
GenomicsChIP-seq of GATA4 in mouse skeletal muscle myoblasts
GATA4 occupancy on the mouse genome of satellite cell-derived primary myoblasts. Proliferating myoblasts cultured in growth medium were immunoprecipitated with anti-GATA4 antibody or control IgG. Precipitated genomic DNAs were subjected to next generation sequencing. Paired-end 150 bp sequence reads...
ORGANISM(S): Mus musculus 
2015-04-10 | E-GEOD-67703 | biostudies-arrayexpress
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