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Effect of Ascorbic acid on human genome
ORGANISM(S): Homo sapiens 
The generation of induced pluripotent stem cells (iPSCs) often results in aberrant silencing of the imprinted Dlk1-Dio3 gene cluster, which compromises their ability to generate entirely iPSC-derived mice (“all-iPSC mice”). Here, we show that reprogramming in the presence of ascorbic acid attenu...
ORGANISM(S): Mus musculus 
The assessment of toxicity about patulin using yeast gene expression comparison analysis. Yeast BY4743 derivative SOD1 mutant was used for this study. Ascorbic acid was used to evaluate the anti-toxic effect to patulin. Keywords: stress response Four series of samples were compared with each by ANOV...
ORGANISM(S): Saccharomyces cerevisiae 
Background: Clear guidelines for therapy of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) are missing due to the lack of randomized double-blind controlled clinical trials. Moderate yet similar clinical benefit has been demonstrated for IFN-a monotherapy and high-dose ascorbic ...
ORGANISM(S): Homo sapiens 
Environmental stimuli-triggered stomatal movement is a key physiological process that regulates CO2 uptake and water loss in plants. Stomata are defined by pairs of guard cells that perceive and transduce external signals, leading to cellular volume changes and consequent stomatal apertur...
2022-01-21 | MTBLS1326 | MetaboLights
Despite advances in investigating functional aspects of osteoblast (OB) differentiation, especially studies on how bone proteins are deposited and mineralized, there has been little research on the intracellular trafficking of bone proteins during OB differentiation. Collagen synthesis and secretio...
ORGANISM(S): Mus musculus 
The effects of a histone demethylase inhibitor, GSK-J4, and L-ascorbic acid for the transcriptome in female ES cells were analyzed by RNA-sequence. Total RNA was used for high-throughput sequence with Illumina HiSeq 2500 and mapped to mm10. Total RNA profile
ORGANISM(S): Mus musculus 
This SuperSeries is composed of the following subset Series: GSE23329: Transcriptome analysis of vtc2, abi4-102 and the corresponding double mutant abi4 vtc2 GSE23330: Transcriptome analysis of vtc1, abi4-102 and wild type Col 0 Refer to individual Series
ORGANISM(S): Arabidopsis thaliana 
The role of abscisic acid (ABA) signalling in the ascorbic acid (AA)-dependent control of plant growth and defence was determined using the vtc1 and vtc2 mutants, which have impaired ascorbic acid synthesis, and in the abi4 mutant that is impaired in ABA-signalling. ABA levels were increase in the m...
ORGANISM(S): Arabidopsis thaliana 
The role of abscisic acid (ABA) signalling in the ascorbic acid (AA)-dependent control of plant growth and defence was determined using the vtc1 and vtc2 mutants, which have impaired ascorbic acid synthesis, and in the abi4 mutant that is impaired in ABA-signalling. ABA levels were increase in the m...
ORGANISM(S): Arabidopsis thaliana 
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