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TranscriptomicsRNAi profiling by array of human U-2-OS osteosarcoma cells with knockdown of Asf1a and Asf1b
We used RNAi to knock-down the two isoforms of Asf1, Asf1a and Asf1b, in human U-2-OS osteosarcoma cells. We obtained two replicates each with siRNAs against Asf1a, Asf1b, combined siRNAs against both isoforms, and two control samples. For these samples, we measured genome-wide transcription levels ...
ORGANISM(S): Homo sapiens 
2011-01-01 | E-MEXP-2671 | biostudies-arrayexpress
ProteomicsASF1B promotes gastric cancer liver metastasis through inhibiting ZDHHC9/PCBP1/ SLC7A11 signaling axis mediated ferroptosis
Despite advances in comprehensive gastric cancer (GC) therapies, the prognosis of patients with liver metastasis remains poor. Identifying potential molecular targets for GC liver metastasis (GCLM) may provide new treatment avenues. Initially, clinical samples from patients with GCLM were analyzed t...
ORGANISM(S): Homo Sapiens 
PXD069269 |
UnknownASF1B promotes cervical cancer progression through stabilization of CDK9.
Not available
S-EPMC7449975 | biostudies-literature
UnknownASF1B acted as a prognostic biomarker for stomach adenocarcinoma.
Not available
S-EPMC10695504 | biostudies-literature
UnknownASF1B Promotes Oncogenesis in Lung Adenocarcinoma and Other Cancer Types.
Not available
S-EPMC8459715 | biostudies-literature
UnknownIncreased ASF1B Expression Correlates With Poor Prognosis in Patients With Gliomas.
Not available
S-EPMC9298524 | biostudies-literature
GenomicsHistone chaperon ASF1B recruits distinct epigenetic factors in regulation of histone variant H3.3 during the fetal and adult erythropoiesis II
Histone chaperon ASF1B recruits distinct epigenetic factors in regulation of histone variant H3.3 during the fetal and adult erythropoiesis II
PRJNA1206179 | ENA
GenomicsHistone chaperon ASF1B recruits distinct epigenetic factors in regulation of histone variant H3.3 during the fetal and adult erythropoiesis.
Histone chaperon ASF1B recruits distinct epigenetic factors in regulation of histone variant H3.3 during the fetal and adult erythropoiesis.
PRJNA888362 | ENA
GenomicsHistone chaperon ASF1B recruits distinct epigenetic factors in regulation of histone variant H3.3 during the fetal and adult erythropoiesis [ChIP-seq]
To identify the role of ASF1B in regulation of histone modification during murine erythropoiesis, H3K27ac and H3.3 ChIP-seq was performed in the WT and ASF1B KO E14.5 fetal liver and bone marrow cells. ASF1B was found bind to the promoter and potential enhancer region. Loss of ASF1B impaired H3.3 an...
ORGANISM(S): Mus musculus 
2026-05-15 | GSE214527 | GEO
GenomicsHistone chaperon ASF1B recruits distinct epigenetic factors in regulation of histone variant H3.3 during the fetal and adult erythropoiesis [ATAC-seq]
To determine ASF1B function in chromatin accessbility, ATAC Seq was performed in both WT and ASF1B KO mouse liver. Loss of ASF1B caused generally decresed of chrmoatin accessbility on the promoters.
ORGANISM(S): Mus musculus 
2026-05-15 | GSE214526 | GEO
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