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ProteomicshSSB1 DNA-binding is modulated by dynamic DNA-PK-mediated phosphorylation
The maintenance of genomic stability is essential for cellular viability and the prevention of diseases such as cancer. Human single-stranded DNA binding protein 1 (hSSB1) is a protein with roles in the stabilisation and restart of stalled DNA replication forks, as well as in the repair of oxidative...
ORGANISM(S): Homo sapiens (Human) 
2018-02-07 | PXD003964 | Pride
Human / hssb1 / dna-pk / ppp family phosphatase / replication stress / hydroxyurea / sciex 5600 
TranscriptomicsTranscriptomic modulation by adenosine 2A receptors in normal and endotoxemic myocardium
Analysis of venticular myocardium from adenosine 2A receptors (A2AR) knockouts following LPS stimulation. Results provide insight into the molecular components of A2AR mediated protection, but also reveal pathogenetic components of endotoxemic myocarditis as a result of LPS exposure. These findings ...
ORGANISM(S): Mus musculus 
2013-05-01 | E-GEOD-44363 | biostudies-arrayexpress
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