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ProteomicsMass spectrometry identification and systems analysis of cytosolic protein N- lysine methylation in anucleate blood platelets
Here, we characterize the methyl-lysine (meK) proteome of anucleate blood platelets. With high-resolution, multiplex mass spectrometry methods, we identify 190 mono-, di- and tri-meK modifications on 150 different platelet proteins, including 28 quantifiable meK modifications consistently present in...
ORGANISM(S): Homo sapiens (Human) 
2019-04-18 | PXD012217 | Pride
Isobaric labeling Lysine methylation  methyllysine  methylation  platelets  post-translational modifications Tandem mass tags 
ProteomicsIntegrated phosphoproteomic profiling and causal analysis reveal signaling relations in GPVI/ITAM-mediated platelet activation programs
Platelets engage cues of pending endothelial dysfunction through coordinated adhesion, secretion and aggregation responses. These rapid changes in platelet phenotype are orchestrated by intracellular mechanisms that remain systematically undefined. This study develops a TMT-SPS-MS3 phosphoproteomics...
ORGANISM(S): Homo sapiens (Human) 
2020-11-20 | PXD017167 | Pride
Human Platelets Causal pathways Cardiovascular disease Isobaric labeling Activation Phosphopeptide enrichment Quantitative proteomics Signaling 
UnknownAssociation of Kidney Comorbidities and Acute Kidney Failure With Unfavorable Outcomes After COVID-19 in Individuals With the Sickle Cell Trait.
Not available
S-EPMC9237798 | biostudies-literature
UnknownGlobal anaesthesia practice using inguinal hernia surgery as a tracer condition: a secondary analysis of an international prospective cohort study.
Not available
S-EPMC12519944 | biostudies-literature
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