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TranscriptomicsTumoral transcriptome profiling of tPTEN-/- mice.
tPTEN-/- mice display a deletion of the PTEN tumor suppressor gene specifically in T cells (cross PTEN flox/flox x lck-Cre). They develop T cell lymphoma with a primary thymic tumor and invasion of most organ at late stage of the disease. Gene profiling was performed on whole tumors (ST3 stage 3 inv...
ORGANISM(S): Mus musculus 
2014-02-03 | E-GEOD-39591 | biostudies-arrayexpress
UnknownRUNX1-dependent RAG1 deposition instigates human TCR-δ locus rearrangement.
Not available
S-EPMC4144731 | biostudies-literature
UnknownTREC mediated oncogenesis in human immature T lymphoid malignancies preferentially involves ZFP36L2.
Not available
S-EPMC10332067 | biostudies-literature
UnknownFirst report of successful pregnancies after treatment with alpelisib for PIK3CA-related overgrowth spectrum.
Not available
S-EPMC12322174 | biostudies-literature
UnknownTargeting the TNF/IAP pathway synergizes with anti-CD3 immunotherapy in T-cell acute lymphoblastic leukemia.
Not available
S-EPMC11143533 | biostudies-literature
UnknownAdult T cell leukemia aggressivenness correlates with loss of both 5-hydroxymethylcytosine and TET2 expression.
Not available
S-EPMC5581026 | biostudies-literature
UnknownImpact of T-cell Receptor Status on Mutational Landscape and Outcome in T-ALL.
Not available
S-EPMC10027033 | biostudies-literature
UnknownPrognostic impact of the PredicT-ALL classifier in the AALL0434 trial: a model combining NGS, MRD, and WBC at diagnosis.
Not available
S-EPMC12552940 | biostudies-literature
UnknownDirect interaction of Ikaros and Foxp1 modulates expression of the G protein-coupled receptor G2A in B-lymphocytes and acute lymphoblastic leukemia.
Not available
S-EPMC5323203 | biostudies-literature
UnknownPRC2 loss of function confers a targetable vulnerability to BET proteins in T-ALL.
Not available
S-EPMC9642784 | biostudies-literature
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