Aspartic proteases

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Unknown (207)
Proteomics (27)
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Organisms

Homo sapiens (2)
Caenorhabditis elegans (1)

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pride (19)
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Disease

Chagas disease (2)
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Mass Spectrometry (19)
Shotgun proteomics (12)
Data-dependent acquisition (5)
Bottom-up proteomics (3)
Illumina HiSeq 2500 (1)
NMR spectroscopy (1)
Mass spectrometry (1)
Affinity purification coupled with mass spectrometry proteomics (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)
Gel-based experiment (1)
HDMSE (1)
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Instrument Platform

Q Exactive (2)
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Liquid Chromatography MS - Negative (LC-MS (Negative)) (1)
Liquid Chromatography MS - Positive (LC-MS (Positive)) (1)
Nuclear Magnetic Resonance (NMR) - (1)

Publication Date

2024 (6)
2018 (6)
2023 (4)
2025 (3)
2026 (3)
2013 (2)
2010 (2)
2008 (2)
2016 (2)
2019 (2)
2014 (1)
2012 (1)
2011 (1)
2007 (1)
2006 (1)
2021 (1)
2020 (1)
2017 (1)
2022 (1)

CHEBI ID

CHEBI:16857 (2)
CHEBI:16010 (2)
CHEBI:16695 (2)
CHEBI:30915 (2)
CHEBI:16761 (2)
CHEBI:16027 (2)
CHEBI:16335 (2)
CHEBI:15354 (2)
CHEBI:141447 (1)
CHEBI:141426 (1)
CHEBI:32401 (1)
CHEBI:73806 (1)
CHEBI:141391 (1)
CHEBI:15405 (1)
CHEBI:141390 (1)
CHEBI:141442 (1)
CHEBI:141407 (1)
CHEBI:141406 (1)
CHEBI:141403 (1)
CHEBI:141412 (1)
CHEBI:141452 (1)
CHEBI:7524 (1)
CHEBI:73803 (1)
CHEBI:74709 (1)
CHEBI:141404 (1)
CHEBI:141411 (1)
CHEBI:74868 (1)
CHEBI:73847 (1)
CHEBI:141393 (1)
CHEBI:90330 (1)

Metabolite Name

L-Threonine (2)
Choline (2)
Adenosine (2)
Quercetin 3-O-glucoside 7-O-rhamnoside (1)
Kaempferol 3-O-glucoside 7-O-rhamnoside (1)
S-Adenosyl methionine (1)
4-[(2E)-3,7-dimethyl-5-oxoocta-2,6-dienyl]-3-methylideneoxolan-2-one (1)
Pyridoxamine-5'-phosphate (1)
4-hydroxy-4-[(E)-3-hydroxybut-1-enyl]-3,5,5-trimethylcyclohex-2-en-1-one (1)
(2E)-11-Hydroxy-2-dodecenoic acid (1)
N-epsilon,N-epsilon,N-epsilon-Trimethyllysine (1)
Alpha-aminopimelic acid (1)
N-Acetyl-L-ornithine (1)
Fenchyl alcohol (1)
Pyridoxol (1)
L-Methionine methylsulfonium (1)
N-(2-Hydroxyethyl)-beta-alanine (1)
Beta-Hydroxynorvaline (1)
3,4-Dimethylaniline (1)
Gamma-Amino-beta-hydroxybutyric acid (1)
(R)-2-Aminobutanoic acid (1)
2',3'-Cyclic Adenosine monophosphate (1)
Alpha-D-Talose (1)
2-Aminobutyrate (1)
L-Lysyl-L-proline (1)
O-Acetylcholine (1)
4-Aminobutyrate (1)
Propargylglycine (1)
Met-Tyr (1)
Tyr-Gln (1)

First Public Date

2014 (2)
2025 (1)
2024 (1)
2019 (1)

Study type

Transcription profiling by array (8)
RNA-seq of coding RNA (1)

Release Date

2021 (18)
2020 (16)
2023 (15)
2016 (15)
2025 (13)
2022 (13)
2017 (13)
2024 (12)
2014 (11)
2011 (11)
2019 (11)
2015 (11)
2013 (8)
2012 (8)
2010 (6)
2018 (6)
2009 (6)
2004 (5)
2007 (4)
2008 (3)
2026 (2)
2005 (2)
2001 (2)
2000 (2)
2006 (1)
2003 (1)
1997 (1)

Lab affiliation

1Laboratory of Vector-Pathogen Biology, Proteomic Platform, Departmet of Molecular Biology, Université Libre de Bruxelles (1)
BOKU University, Department of Agricultural Sciences, Institute of Environmental Biotechnology (1)
CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-517 Coimbra, Portugal; Biocant, Biotechnology Innovation Center, 3060-197 Cantanhede, Portugal; (1)
Connie Jimenez, OncoProteomics Laboratory, Dept of Medical Oncology, Amsterdam University Medical Centers, Amsterdam, The Netherlands (1)
DZNE Munich, Neuroproteomics, Feodor-Lynen Str. 17, 81377 Munich, Germany (1)
Department of Molecular Biology, Sc III, University of Geneva (1)
Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute, Jena, Germany (1)
Deputy Director – Science Strategy The Walter and Eliza Hall institute of Medical Research Professor, Department of Medical Biology Faculty of Medicine, Dentistry and Health The University of Melbourne Australia (1)
Eppley Institute University of Nebraska Medical Center (1)
Ghent University (1)
IBCH RAS (1)
Laboratory of Molecular Biology of Bacterial Pathogens, Institute of Microbiology, Czech Academy of Sciences (1)
Laboratory of Organic Mass Spectrometry, Department of Chemical Sciences, University of Catania (1)
Laboratory of Vector-Pathogen Biology, Proteomic Platform, Department of Molecular Biology, Université Libre de Bruxelles (1)
Manchester Institute of Biotechnology, School of Biological Sciences, Manchester Academic Health Sciences Centre, The University of Manchester, Princess Street, Manchester, M1 7DN, UK (1)
Plant Biotechnology, Faculty of Biology, University of Freiburg, Schaenzlestr.1, D-79104 Freiburg, Germany (1)
Regional Medical Research Centre, Indian Council of Medical Research, Port Blair, India (1)
Umeå Plant Science Centre, Department of Plant Physiology, Umeå University, 90187 Umeå, Sweden (1)
University Medicine Greifswald, Institute of Medical Biochemistry and Molecular Biology (1)

Tags

xref:PubMed:40291136 (1)

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Expression profile of Rhodnius prolixus midgut associated-aspartic proteases

Monitoring of expression pattern of Rhodnius prolixus A1 aspartic proteases after their enrichment by pepstatin A affinity chromatography from the anterior midgut tissue.

ORGANISM(S): Rhodnius prolixus (Triatomid bug)

2024-04-28 | PXD044628 | Pride

Multiple aspartic proteases process PE and PPE proteins on the mycobacterial surface of pathogenic mycobacteria

Mycobacterium tuberculosis is the world’s leading bacterial infectious agent. The absence of an effective vaccine and the rise of multi-drug resistant M. tuberculosis strains emphasize the need to identify novel targets for prevention and intervention strategies. Previously, the M. marinum orthologu...

ORGANISM(S): Mycobacterium marinum ATCC BAA-535

2026-08-19 | PXD067990 | Pride

Mycobacterium marinum Aspartic acid protease Substrate specificity

Aspartic proteases of Plasmodium vivax are highly conserved in wild isolates.

Not available

S-EPMC2717343 | biostudies-literature

Anthelmintic Potential of Aspartic Proteases Inhibitors

PRJNA840851 | ENA

Biochemical characterization of two new Aspergillus niger aspartic proteases.

Not available

S-EPMC7293714 | biostudies-literature

Cocaprins, β-Trefoil Fold Inhibitors of Cysteine and Aspartic Proteases from Coprinopsis cinerea.