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TranscriptomicsComparison of the transcriptome of day 3 human embryo with that of the trophectoderm
In humans, the embryonic genome activation (EGA) program is functional by day 3 after fertilization. The 6-8 cell stage embryo (day 3 post-fertilization) starts the process of “compaction” that leads to the generation of the tightly organized cell mass of the morula and is followed by differentiatio...
ORGANISM(S): Homo sapiens 
2012-07-08 | E-GEOD-33025 | biostudies-arrayexpress
TranscriptomicsSmall RNA profiling of human cumulus cells and oocytes
Cumulus cells are biologically distinct from other follicular cells and perform specialized roles, transmitting signals within the ovary and supporting oocyte maturation during follicular development. The bi-directional communication between the oocyte and the surrounding cumulus cells is crucial fo...
ORGANISM(S): Homo sapiens 
2015-04-10 | E-GEOD-44792 | biostudies-arrayexpress
TranscriptomicsHuman cumulus cells
Cumulus cells (CCs) are biologically distinct from other follicular cells and perform specialized roles, transmitting signals within the ovary and supporting oocyte maturation during follicular development. The Affymetrix 3’ IVT express protocol was used to prepare cRNA (one-cycle amplification) wit...
ORGANISM(S): Homo sapiens 
2012-03-10 | E-GEOD-31681 | biostudies-arrayexpress
TranscriptomicsDys and Eureprogramming
Pluripotent stem cells have the potential to differentiate in vitro in many, if not all, functional cell types. Induced pluripotent stem cells (iPS) have recently emerged as a reproducible model of pluripotent stem cells that can be generated from post-natal tissues. To understand this process at th...
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-18147 | biostudies-arrayexpress
TranscriptomicsGeneration of pluripotent stem cells
Pluripotent stem cells, which are capable to generate any cell type of the human body, such as human embryonic stem cells (hESC) or human induced pluripotent stem cells (hiPS) are a very promising source of cells for regenerative medicine. However, the genesis, the in vitro amplification and the dif...
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-15491 | biostudies-arrayexpress
TranscriptomicsHematopietic system high resolution transcriptome
Recent advances in high density oligonucleotides microarray technology have generated solutions for molecular profiling of human samples at an unprecedented resolution. We mapped whole blood RNA from healthy volunteers and CD34+ collected by cytapheresis from patients to Exon ST 1.0 microarray probi...
ORGANISM(S): Homo sapiens 
2010-04-08 | E-GEOD-10480 | biostudies-arrayexpress
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