Asymmetric division

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Metabolite Name

Alpha (1)
Aldehydo-D-ribose 5-phosphate (1)
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N(6) (1)
(R)-mevalonic acid (1)
2-amino-2-deoxy-D-glucopyranose (1)
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PS 36:5 (1)
PI 20:4-20:4 (1)
PI 18:1-22:6 (1)
PI 18:0-22:6 (1)
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PI 16:0-18:0 (1)
PI 14:0-18:0 (1)
PG 22:6-22:6 (1)
PE O-40:8 (1)
PE O-18:1/22:6 (1)
PE O-20:0/20:4 (1)
PE O-38:4 (1)
PE O-38:2 (1)

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Modelling Approach

Ordinary differential equation model (5)
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Lab affiliation

Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Department of Medicine, Brigham Women's Hospital, Harvard Medical School, Boston, MA, United States (2)
Bertis R&D Division, Bertis Inc., Republic of Korea (1)
Carnegie Mass Spectrometry Facility (1)
Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Department of Medicine, Brigham Women's Hospital, Harvard Medical School, Boston, MA, 02115, United States (1)
Department of Cancer Biology, Dana-Farber Cancer Institute Department of Cell Biology, Harvard Medical School (1)
Director of Carnegie MS facility (1)
Division of Gastroenterology, Boston Children's Hospital and Harvard Medical School, 300 Longwood Ave., Boston, MA 02115, USA (1)
Head of Proteomics (1)
IEO, European Institute of Oncology IRCCS, Via Adamello 16, 20139 Milan, Italy. (1)
Institut I für Anatomie AG Molekulare Zellbiologie Universität zu Köln Kerpener Str. 62, Geb. 37 D-50937 Cologne Germany (1)
Institute of Biotechnology, PO Box 56,00014 University of Helsinki, Finland Karolinska Institutet, Department of Cell and Molecular Biology, Tomtebodavägen 16,Biomedicum, SE-171 65 Solna, Sweden (1)
Kennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom (1)
Laboratory of Molecular Biology (1)
Leibniz Institute on Aging - Fritz Lipmann Institute FLI (1)
MRC Protein Phosphorylation & Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK (1)
Research Group Bioanalytical Mass Spectrometry, Max Planck Institute for Multidisciplinary Sciences, Germany; Bioanalytics, Department of Clinical Chemistry, University Medical Center Goettingen, Germany (1)
Shanghai Normal University, China (1)
Srikant Rangaraju, MD MS Associate Professor Department of Neurology Vascular Neurology Division Emory University (1)
The Francis Crick Institute (1)
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IsPrivate

False (6)

Submitter Keywords

Immuno-oncology (1)

Study type

Transcription profiling by array (41)
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Other (2)
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Release Date

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Asymmetric cancer cell division regulated by AKT, Reactive Oxygen Species (ROS) high versus ROS low mRNA

Human tumors often contain slowly proliferating cancer cells that resist treatment but we do not know precisely how these cells arise. We show that rapidly proliferating cancer cells can divide asymmetrically to produce slowly proliferating “G0-like” progeny that are enriched following chemotherapy ...

ORGANISM(S): Homo sapiens

2011-07-14 | E-GEOD-30465 | biostudies-arrayexpress

Asymmetric self-renewal associated (ASRA) genes

Cell lines geneticially engineered to undergo conditional asymmetric self-renewal were used to identify genes whose expression is asymmetric self-renewal associated (ASRA). Non-random sister chromatid segregation occurs concordantly with asymmetric self-renewal in these cell lines. Asymmetric self-...

ORGANISM(S): Mus musculus

2010-12-22 | E-GEOD-25334 | biostudies-arrayexpress

Gene expression of CD8 T cell progenies generated via asymmetric cell division

Asymmetric partitioning of fate-determinants is a mechanism that contributes to T cell differentiation. However, it remained unclear whether the ability of T cells to divide asymmetrically is influenced by their differentiation state, as well as if enforcing asymmetric cell division rates would have...

ORGANISM(S): Mus musculus

2019-02-14 | E-MTAB-7651 | biostudies-arrayexpress

The SHR/SCR pathway directly activates genes involved in asymmetric cell division in the Arabidopsis root

Asymmetric division of cortex/endodermal initials (CEI) in the Arabidopsis root generates two layers of ground tissue and is controlled by a finely orchestrated interplay between the transcription factors, SHORT ROOT (SHR) and SCARECROW (SCR). To understand the dynamics of the SHR/SCR regulatory ne...

ORGANISM(S): Arabidopsis thaliana

2010-07-19 | E-GEOD-15876 | biostudies-arrayexpress

Genes required for aerial growth, cell division, and chromosome segregation are targets of WhiA before sporulation in Streptomyces venezuelae.

WhiA is a highly unusual transcriptional regulator related to a family of eukaryotic homing endonucleases. WhiA is required for sporulation in the filamentous bacterium Streptomyces, but WhiA homologues of unknown function are also found throughout the Gram-positive bacteria. To better understand th...

ORGANISM(S): Streptomyces venezuelae

2016-05-20 | E-MTAB-4673 | biostudies-arrayexpress

Islr regulates satellite cells asymmetric division through Sparc/p-ERK1/2 signaling pathway

PRJNA868366 | ENA

Fate induction in CD8 chimeric antigen receptor T-cells through asymmetric cell division

PRJNA1119378 | ENA

Gene expression of CD8 T cell progenies generated via asymmetric cell division

PRJEB31160 | ENA

APT1 regulates the asymmetric partitioning of Notch and Wnt signaling during cell division

PRJNA415217 | ENA

Asymmetric division in a two-cell-like state rejuvenates embryonic stem cells

PRJNA1211501 | ENA