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GenomicsDiscovery of Transcription Factors and Regulatory Regions Driving In Vivo Tumor Development by ATAC-seq and FAIRE-seq Open Chromatin Profiling
Genomic enhancers regulate spatio-temporal gene expression by recruiting specific combinations of transcription factors (TFs). When TFs are bound to active regulatory regions, they displace canonical nucleosomes, making these regions biochemically detectable as nucleosome-depleted regions or accessi...
ORGANISM(S): Drosophila melanogaster 
2015-02-13 | E-GEOD-59078 | biostudies-arrayexpress
GenomicsATAC-seq Analysis in Control and Mier1 KO Mice Liver at 0 h and 24 h after 70% Partial Hepatectomy
ATAC-seq Analysis in Control and Mier1 KO Mice Liver at 0 h and 24 h after 70% Partial Hepatectomy
PRJNA876292 | ENA
TranscriptomicsSingle cell ATAC-seq of human peripheral blood mononuclear cells under resting and stimulated conditions
Single cell ATAC-seq of PBMC - resting and stimulated. Used for comparison to asses the capabilies of the five-prime sequencing method in the detection of cis-regulatory elements using SCAFE (see publication).
ORGANISM(S): Homo sapiens 
2021-04-13 | E-MTAB-10382 | biostudies-arrayexpress
TranscriptomicsATAC-seq of iPSC and human dermal fibroblasts
ATAC-seq of iPSC and human dermal fibroblasts, used to compare open chromatin and transcription signal.
ORGANISM(S): Homo sapiens 
2021-05-02 | E-MTAB-10381 | biostudies-arrayexpress
GenomicsATAC-seq of Oesophageal Cell Lines
ATAC-seq in oesophageal cell lines, OE33 (OAC), FLO1 (OAC), HET1A (Normal)
ORGANISM(S): Homo sapiens 
2016-09-12 | E-MTAB-4209 | biostudies-arrayexpress
TranscriptomicsATAC-seq of oesophageal adenocarcinoma cell line MFD-1
The open chromatin of new esophageal adenocarcinoma cell line MFD-1 has been profiled by ATAC-seq.
ORGANISM(S): Homo sapiens 
2018-04-06 | E-MTAB-6720 | biostudies-arrayexpress
TranscriptomicsATAC-seq of HepG2 cells
ATAC-seq open chromatin maps for HepG2 cells (3 biological replicates), a liver model.
ORGANISM(S): Homo sapiens 
2019-03-20 | E-MTAB-7543 | biostudies-arrayexpress
TranscriptomicsSu(H) bound regions in Su(H) induced wing-disc hyperplasia
The outcome of Notch activation on proliferation depends on cellular context. In Drosophila wing discs Notch activation causes hyperplasia despite having localized inhibitory effects on proliferation. To understand the underlying mechanisms we have used genomic strategies to identify the Notch-Su(H)...
ORGANISM(S): Drosophila melanogaster 
2013-12-31 | E-GEOD-41425 | biostudies-arrayexpress
TranscriptomicsATAC-seq of mouse bone-marrow–derived macrophages and osteoclast precursors (BMM, RANKL-16h, RANKL-36h) from wild-type and Senp6 conditional knockout mice
To examine the impaired osteoclastogenic program in Senp6^LysM BMMs, we performed ATAC-seq on WT and Senp6^LysM BMMs stimulated with RANKL for 0 h (R0), 16 h (R16), and 36 h (R36), corresponding to sequential stages of early osteoclastogenesis.
ORGANISM(S): Mus musculus 
2026-09-28 | E-MTAB-16167 | biostudies-arrayexpress
GenomicsRegulatory regions of MCF10A before and after H-RAS transformation [ATAC-seq]
Regulatory regions of MCF10A before and after H-RAS transformation [ATAC-seq]
PRJNA589054 | ENA
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