Sort   by:  
 Page size 
GenomicsPolycomb dysregulation in gliomagenesis targets a Zfp423-dependent differentiation network [ChIP-Seq]
Malignant gliomas constitute one of the most significant areas of unmet medical need, due to the invariable failure of surgical eradication and their marked molecular heterogeneity. Accumulating evidence has revealed a critical contribution by the Polycomb axis of epigenetic repression. However, a c...
ORGANISM(S): Mus musculus 
2016-03-02 | E-GEOD-76289 | biostudies-arrayexpress
TranscriptomicsPolycomb dysregulation in gliomagenesis targets a Zfp423-dependent differentiation network [RNA-Seq]
Malignant gliomas constitute one of the most significant areas of unmet medical need, due to the invariable failure of surgical eradication and their marked molecular heterogeneity. Accumulating evidence has revealed a critical contribution by the Polycomb axis of epigenetic repression. However, a c...
ORGANISM(S): Mus musculus 
2016-03-02 | E-GEOD-76291 | biostudies-arrayexpress
Transcriptomics7q11.23 dosage-dependent dysregulation in the human pluripotent state primes aberrant transcriptional programs in disease-relevant lineages (microarray)
We apply the cellular reprogramming experimental paradigm to two disorders caused by symmetrical copy number variations (CNV) of 7q11.23 and displaying a striking combination of shared as well as symmetrically opposite phenotypes: Williams Beuren syndrome (WBS) and 7q microduplication syndrome (7dup...
ORGANISM(S): Homo sapiens 
2014-12-15 | E-GEOD-63040 | biostudies-arrayexpress
Sort   by:  
 Page size