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MetabolomicsMetabolomic determinants of carotid atherosclerosis plaque stability
Our objective is to identify the metabolites associated with stability of carotid atheromatous plaques compared to vulnerable plaques, through a metabolomic approach. Eighty consecutive patients with carotid artery stenosis (CAS) who underwent carotid endarterectomy (CEA) according to current guidel...
2025-06-06 | MTBLS12303 | MetaboLights
MetabolomicsOral-gut microbiome and plasma metabolome reveal incremental restratification of coronary artery disease from the clinical gray zone
Clinical prediction models have been widely applied for risk stratification of coronary artery disease (CAD), yet approximately 20% to 40% of screened individuals fall into the intermediate-risk interval and face a decision gap. Here, we adopted a two-stage validation design. In the first stage, a c...
2026-08-31 | MTBLS15425 | MetaboLights
TranscriptomicsCardiac gene expression profiling of apoE-deficient mice receiving heart failure treatment with the anti-ischemic drug ranolazine
Heart failure is a leading cause of cardiovascular mortality with limited options for treatment. We used 18 month-old apolipoprotein E (apoE)- deficient mice as a model of atherosclerosis-induced heart failure to analyze whether the anti-ischemic drug ranolazine could retard the progression of heart...
ORGANISM(S): Mus musculus 
2010-12-03 | E-GEOD-25767 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human coronary arteries from patients with and without collateral artery vessels to identify novel markers of coronary collateralization
Evaluation of transcriptional regulation in Coronary artery disease patients with and without collateral artery vessels.
ORGANISM(S): Homo sapiens 
2006-03-10 | E-MEXP-564 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human Hutchinson-Gilord progeria syndrome fibroblast cell lines with dominant mutation in the LMNA gene and age-matched normal controls
Hutchinson-Gilford progeria syndrome (HGPS) is a rare genetic disease with widespread phenotypic features resembling premature aging. HGPS was recently shown to be caused by dominant mutations in the LMNA gene, resulting in the in-frame deletion of 50 amino acids near the carboxyl terminus of the en...
ORGANISM(S): Homo sapiens 
2007-12-12 | E-GEOD-3860 | biostudies-arrayexpress
GenomicsPerivascular adipose tissue inflammation in ischemic heart disease
Perivascular adipose tissue inflammation in ischemic heart disease
PRJNA638962 | ENA
GenomicsCirculating angiogenic profiles in ischemic stroke and intracranial atherosclerosis (ICAD)
Circulating angiogenic profiles in ischemic stroke and intracranial atherosclerosis (ICAD)
PRJNA1380502 | ENA
UnknownVitamin K-Dependent Protein Activity and Incident Ischemic Cardiovascular Disease: The Multi-Ethnic Study of Atherosclerosis.
Not available
S-EPMC5844474 | biostudies-literature
UnknownSpecific P-selectin and P-selectin glycoprotein ligand-1 genotypes/haplotypes are associated with risk of incident CHD and ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) study.
Not available
S-EPMC2175083 | biostudies-literature
UnknownPsychosocial factors and subsequent risk of hospitalizations with peripheral artery disease: The Atherosclerosis Risk in Communities (ARIC) Study.
Not available
S-EPMC8277672 | biostudies-literature
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