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MetabolomicsEarly-life skin molecular signatures are predictive of atopic dermatitis risk in an Asian preconception birth cohort
Rationale: Early identification of infants at risk for atopic dermatitis (AD) is critical for timely prevention, yet robust preclinical biomarkers remain elusive. We characterized the longitudinal evolution of the skin microbiome, metabolome, and proteome to identify molecular signatures predictive ...
2026-10-05 | MTBLS14496 | MetaboLights
MetabolomicsUntargeted cecal metabolomic profiling in MC903-induced atopic dermatitis-like mice orally administered live or heat-killed Ligilactobacillus salivarius Ls.0403
This project characterizes cecal metabolic profiles in an MC903-induced atopic dermatitis-like mouse model following oral administration of live or heat-killed Ligilactobacillus salivarius Ls.0403. Cecal content samples were collected from four experimental groups, including Blank, Model, live Ls.04...
2026-09-03 | MTBLS15541 | MetaboLights
TranscriptomicsmRNA expression of Atopic Dermatitis skin
mRNA array analysis was carried out using total RNA of skin biopsies from lesional and non-lesional skin of three atopic dermatitits patients and four healthy individuals.
ORGANISM(S): Homo sapiens 
2012-06-01 | E-MTAB-729 | biostudies-arrayexpress
MetabolomicsIntegrated metabolomics and lipidomics study of patients with atopic dermatitis in response to dupilumab
Not available
ORGANISM(S): Homo sapiens 
ST002302 | MetabolomicsWorkbench
TranscriptomicsmRNA expression of Atopic Dermatitis keratinocytes
mRNA array analysis of total RNA from primary kertinocytes from three healthy controls, three atopic dermatitis patients and three psoriasis patients was carried out
ORGANISM(S): Homo sapiens 
2012-06-01 | E-MTAB-728 | biostudies-arrayexpress
TranscriptomicsGene Transcription Abnormalities in Canine Atopic Dermatitis
Canine atopic dermatitis (AD) is clinically similar to human AD, implicating it as a useful model of human eosinophilic allergic disease. To identify cutaneous gene transcription changes in relatively early inflammation of canine AD, microarrays were used to monitor transcription in normal skin (n=...
ORGANISM(S): Canis lupus familiaris 
2012-07-11 | E-GEOD-39278 | biostudies-arrayexpress
TranscriptomicsBroad defects in epidermal cornification in atopic dermatitis (AD) identified through genomic analysis
In this study we used genomic profiling to characterize differences in expression of genes related to epidermal growth/differentiation and inflammatory circuits in skin lesions of psoriasis and atopic dermatitis (AD), comparing expression values to normal skin. Skin biopsies were collected from 9 pa...
ORGANISM(S): Homo sapiens 
2009-10-31 | E-GEOD-16161 | biostudies-arrayexpress
TranscriptomicsExpression data for human epithelium from subjects with atopic dermatitis, psoriasis and nonatopic controls
The expression and function of tight junction genes, in particular claudin-1, was studied in order to further understanding of the biology underlying atopic dermatitis. Gene expression profiling was performed on total RNA from nonlesional epidermal samples from 5 subjects with atopic dermatitis, 4 s...
ORGANISM(S): Homo sapiens 
2011-01-29 | E-GEOD-26952 | biostudies-arrayexpress
TranscriptomicsDistinct molecular signatures of mild extrinsic and intrinsic atopic dermatitis
Atopic dermatitis (AD) is a common inflammatory skin disease with underlying defects in epidermal function and immune responses. The goal of this study was to investigate differences in gene expression in lesional skin from patients with mild extrinsic or intrinsic AD compared to skin from healthy c...
ORGANISM(S): Homo sapiens 
2016-03-08 | E-GEOD-75890 | biostudies-arrayexpress
GenomicsThe characteristics of genome-wide DNA methylation in naM-CM-/ve CD4+ T cells of patients with psoriasis and atopic dermatitis
Psoriasis and atopic dermatitis (AD) are characterized by polarized CD4+ T cell responses. During the polarization of naM-CM-/ve CD4+ T cells, DNA methylation plays an important role in the regulation of gene transcription. In this study, we profiled the genome-wide DNA methylation status of naM-CM-...
ORGANISM(S): Homo sapiens 
2012-03-17 | E-GEOD-35582 | biostudies-arrayexpress
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