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TranscriptomicsPosttranscriptional reprogramming controls MASLD progression through chronic ER stress adaptation (RIP Seq)
Metabolic dysfunction-associated steatohepatitis (MASH) and its progression to hepatocellular carcinoma remain major clinical challenges. Chronic endoplasmic reticulum (ER) stress, induced by sustained high-fat diet (HFD) intake, promotes hepatic inflammation, lipid accumulation, and hepatocellular ...
ORGANISM(S): Mus musculus 
2026-03-05 | E-MTAB-16346 | biostudies-arrayexpress
TranscriptomicsPosttranscriptional reprogramming controls MASLD progression through chronic ER stress adaptation (RNAseq 2)
Metabolic dysfunction-associated steatohepatitis (MASH) and its progression to hepatocellular carcinoma remain major clinical challenges. Chronic endoplasmic reticulum (ER) stress, induced by sustained high-fat diet (HFD) intake, promotes hepatic inflammation, lipid accumulation, and hepatocellular ...
ORGANISM(S): Mus musculus 
2026-03-05 | E-MTAB-16294 | biostudies-arrayexpress
TranscriptomicsPosttranscriptional reprogramming controls MASLD progression through chronic ER stress adaptation (RNAseq)
Metabolic dysfunction-associated steatohepatitis (MASH) and its progression to hepatocellular carcinoma remain major clinical challenges. Chronic endoplasmic reticulum (ER) stress, induced by sustained high-fat diet (HFD) intake, promotes hepatic inflammation, lipid accumulation, and hepatocellular ...
ORGANISM(S): Mus musculus 
2026-03-05 | E-MTAB-16295 | biostudies-arrayexpress
TranscriptomicsPosttranscriptional reprogramming controls MASLD progression through chronic ER stress adaptation (Riboseq)
Metabolic dysfunction-associated steatohepatitis (MASH) and its progression to hepatocellular carcinoma remain major clinical challenges. Chronic endoplasmic reticulum (ER) stress, induced by sustained high-fat diet (HFD) intake, promotes hepatic inflammation, lipid accumulation, and hepatocellular ...
ORGANISM(S): Mus musculus 
2026-03-05 | E-MTAB-16293 | biostudies-arrayexpress
TranscriptomicsCRC micrometastasis generated by AKP MTOs resolved by single cell RNAseq
Longitudinal single cell RNA-expression analysis of tumor cells along metastatic relapse. AKP mouse tumor organoids (MTOs) were implanted in the caecum and left to metastasize into the liver. Livers were collected at different timepoints post-injection and GFP+ CD45- cells were sorted in 96-well sma...
ORGANISM(S): Mus musculus 
2022-11-18 | E-MTAB-11981 | biostudies-arrayexpress
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