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TranscriptomicsTranscription profiling of brains from cognitively impaired and unimpaired old rats and young rats at zero or 21 days post water maze training, and untrained individuals
Although immediate early genes (IEGs) such as Bdnf, Arc and Egr1, have been implicated in plasticity, the larger pathways related to memory and memory disorders are not well understood. Here, we combined statistical Affymetrix microarray and behavioral analyses to identify key genes and pathways ass...
ORGANISM(S): Rattus norvegicus 
2007-11-29 | E-GEOD-5666 | biostudies-arrayexpress
UnknownIn Situ Study of Nanoporosity Evolution during Dealloying AgAu and CoPd by Grazing-Incidence Small-Angle X-ray Scattering.
Not available
S-EPMC8900123 | biostudies-literature
MetabolomicsRare and common genetic determinants of metabolic individuality and their effects on human health (EPIC-Norfolk study assays)

Garrod’s concept of “chemical individuality” has contributed to comprehension of the molecular origins of human diseases. Untargeted high-throughput metabolomic technologies provide an in-depth snapshot of human metabolism at scale. We studied the genetic architecture of the human plasma metabolo...

2022-09-09 | MTBLS833 | MetaboLights
MetabolomicsIntegrated gut metabolome and microbiome fingerprinting reveals that dysbiosis precedes allergic inflammation in IgE‐mediated pediatric cow's milk allergy

BACKGROUND: IgE-mediated cow's milk allergy (IgE-CMA) is one of the first allergies to arise in early childhood and may result from exposure to various milk allergens, of which β-lactoglobulin (BLG) and casein are the most important. Understanding the underlying mechanisms behin...

2024-02-15 | MTBLS6768 | MetaboLights
UnknownInfected foot ulcers in male and female diabetic patients: a clinico-bioinformative study.
Not available
S-EPMC2821376 | biostudies-literature
UnknownReappraising Schmidpeter's bis(iminophosphoranyl)phosphides: coordination to transition metals and bonding analysis.
Not available
S-EPMC8178813 | biostudies-literature
UnknownEntropy-Entropy Compensation between the Protein, Ligand, and Solvent Degrees of Freedom Fine-Tunes Affinity in Ligand Binding to Galectin-3C.
Not available
S-EPMC8395690 | biostudies-literature
MetabolomicsDiscovery of urinary biomarkers to discriminate between exogenous and semi-endogenous thiouracil in cattle (Calf samples)
In the European Union, the use of thyreostats for animal fattening purposes has been banned because of their carcinogenic and teratogenic effects, whereby any residues in derived food products may hold a risk for human health. In this regard, potential abuse is monitored by targeted analysis of thyr...
2018-02-22 | MTBLS554 | MetaboLights
MetabolomicsDiscovery of urinary biomarkers to discriminate between exogenous and semi-endogenous thiouracil in cattle (Cow samples)
In the European Union, the use of thyreostats for animal fattening purposes has been banned because of their carcinogenic and teratogenic effects, whereby any residues in derived food products may hold a risk for human health. In this regard, potential abuse is monitored by targeted analysis of thyr...
2018-02-22 | MTBLS561 | MetaboLights
MetabolomicsPharmacokinetic and urinary profiling reveals prednisolone/cortisol ratio as a valid biomarker for prednisolone administration
In Europe, synthetic corticosteroids are not allowed in animal breeding fro growth-promoting purposes. Nevertheless, a high prevalence of non-compliant urine samples was recently reported for prednisolone, however, without any indication of unauthorized use. Within this context, 20b-dihydroprednisol...
2018-01-23 | MTBLS488 | MetaboLights
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