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TranscriptomicsExpression profiles of villus and crypt layers of large intestine from C57Bl/6, Apc1638N+/-, and p21-/- mice.
Expression profiles obtained from the villus and crypt layers of murine large intestine can elucidate the process of differentiation undergone by epithelial cells as they migrate from the undifferentiated bottom of the crypt to the villus tip before being shed into the intestinal lumen. This series...
ORGANISM(S): Mus musculus 
2010-10-06 | E-GEOD-19338 | biostudies-arrayexpress
TranscriptomicsExpression data of small intestine crypts and villi from mice with nutritional and genetic risk factors for intestinal tumors
Nutritional and genetic risk factors for intestinal tumors are additive on mouse tumor phenotypes, demonstrating that diet and genetic factors impact risk by distinct combinatorial mechanisms. We analyzed expression profiles of small intestine crypts and villi from mice with nutritional and genetic ...
ORGANISM(S): Mus musculus 
2011-05-31 | E-GEOD-29538 | biostudies-arrayexpress
TranscriptomicsColon Tumor Cell Macrophage Interactions
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-03-12 | E-GEOD-55811 | biostudies-arrayexpress
TranscriptomicsCell autonomous and non-autonomous interactions of a western-style diet and the vitamin D receptor in intestinal homeostasis and tumorigenesis
These data suggest that co-culture with macrophages increases expression of NDRG-1 in epithelial cell lines. The finding is confirmed in 2 human epithelial cell lines, and in tissue derived from mice genetically and dietetically altered to increase macrophage infiltration of the small and large int...
ORGANISM(S): Mus musculus 
2014-03-12 | E-GEOD-55809 | biostudies-arrayexpress
TranscriptomicsEffect of co-culture with macrophages on two colon cancer cell lines.
These data suggest that co-culture with macrophages increases expression of NDRG-1 in epithelial cell lines. The finding is confirmed in 1 mouse epithelial cell line, and in tissue derived from mice genetically and dietetically altered to increase macrophage infiltration of the small and large inte...
ORGANISM(S): Homo sapiens 
2014-03-12 | E-GEOD-55810 | biostudies-arrayexpress
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