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TranscriptomicsRole of IL-2 inducible T cell kinase (ITK) and Bruton's tyrosine kinase (BTK) in mast cell response to lipopolysaccharide (LPS)
Mast cells are indispensable for LPS-induced septic hypothermia, in which TNF-α plays an essential role to initiate sepsis. Tec family non-receptor tyrosine kinases ITK and BTK regulate mast cell-derived TNF-α in response to allergic antigen, but their role in LPS-induced TNF-α production by mast...
ORGANISM(S): Mus musculus 
2015-11-23 | E-GEOD-64287 | biostudies-arrayexpress
TranscriptomicsDistinguishing innate memory CD8+ T from homeostatically expanded CD8+ T cells
Innate memory phenotype (IMP) CD8+ T cells are non-conventional αβ T cells exhibiting features of innate immune cells, and are significantly increased in the absence of non-receptor tyrosine kinase ITK. Their developmental path and function are not clear, particularly whether they can contribute to ...
ORGANISM(S): Mus musculus 
2013-02-19 | E-GEOD-41482 | biostudies-arrayexpress
TranscriptomicsGenerating mouse model with predominant naïve or innate memory phenotype CD4+ T cells
Innate memory phenotype (IMP) CD4+ T cells are non-conventional αβ T cells exhibiting features of innate immune cells, characterized as CD44high and CD62Llow in periphery. It is recently reported by our group that bone marrow chimeric mice lacking thymic MHCI expression develop predominantly IMP C...
ORGANISM(S): Mus musculus 
2014-03-14 | E-GEOD-46892 | biostudies-arrayexpress
UnknownEnhanced development of CD4+ gammadelta T cells in the absence of Itk results in elevated IgE production.
Not available
S-EPMC2713465 | biostudies-literature
UnknownClinical Use of Tecovirimat (Tpoxx) for Treatment of Monkeypox Under an Investigational New Drug Protocol - United States, May-August 2022.
Not available
S-EPMC9484807 | biostudies-literature
UnknownThe Effect of Prebiotics and Oral Anti-Diabetic Agents on Gut Microbiome in Patients with Type 2 Diabetes: A Systematic Review and Network Meta-Analysis of Randomised Controlled Trials.
Not available
S-EPMC9739188 | biostudies-literature
UnknownDesign features that reduce the use of seclusion and restraint in mental health facilities: a rapid systematic review.
Not available
S-EPMC8264870 | biostudies-literature
GenomicsMus musculus
Generating mouse model with predominant naïve or innate memory phenotype CD4+ T cells
PRJNA202971 | ENA
GenomicsMus musculus
Distinguishing innate memory CD8+ T from homeostatically expanded CD8+ T cells
PRJNA177166 | ENA
UnknownCurrent Advances and Future Prospects in the Use of a Low-Carbohydrate Diet in Managing People with Type 2 Diabetes: A Systematic Review of Randomised Controlled Trials.
Not available
S-EPMC12469876 | biostudies-literature
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