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Transcriptomic analysis of mouse embryonic stem cells (mESC) maintained in the pluripotent state or allowed to differentiate for 3 or 7 days by leukaemia inhibitory factor (LIF) withdrawal.
ORGANISM(S): Mus musculus 
Galectin-1 (Gal-1) and Galectin-3 (Gal-3) are conserved carbohydrate-binding proteins that also display RNA-binding activity. We generated mouse embryonic stem cells (mESC) constitutively depleted of Gal-1 and/or Gal-3 using CRISPR-Cas9, and assessed the transcriptomic effects of the individual or c...
ORGANISM(S): Mus musculus 
Galectin-3 (Gal-3) has emerged as a novel RNA-binding protein. Here we applied eCLIP to identify the RNAs bound by Gal-3 in mouse embryonic stem cells differentiated by deprivation of the leukaemia inhibitory factor (LIF) for 7 days.
ORGANISM(S): Mus musculus 
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