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TranscriptomicsTranscription profiling of rat fibroblast-like synoviocyte cell cultures treated with TNFa and SB203580
Gene expression affected by TNFa was investigated, then, p38 inhibitor SB203580 was used to investigate p38 signal pathway. Experiment Overall Design: Fibroblast-like synoviocyte culture was treated with TNFa in the presence and absence of SB203580 and compared to the gene expression not treated wi...
ORGANISM(S): Rattus norvegicus 
2008-06-15 | E-GEOD-7826 | biostudies-arrayexpress
TranscriptomicsSelection for improved energy efficiency and drought tolerance in canola results in distinct transcriptome and epigenome changes [RNA-Seq]
Integrated breeding strategies are used to increase both the yield potential and stability of crops. Most of these approaches have a direct genetic basis. The utility of epigenetics in breeding to improve complex traits such as yield and stress tolerance is not clear. A better understanding of th...
ORGANISM(S): Brassica napus 
2015-06-28 | E-GEOD-65572 | biostudies-arrayexpress
TranscriptomicsComparison of transcriptome of in vitro and in vivo-produced bovine fetuses; specifically in liver and placental tissues.
During the past several decades, in vitro fertilization (IVF) has been increasingly used both in animal production and human infertility treatment. Animals derived from in vitro manipulation are occasionally associated with abnormal offspring syndrome (AOS) and other developmental abnormalities. By ...
ORGANISM(S): Bos taurus 
2011-07-25 | E-GEOD-29987 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse hematopoietic cells at different differentiation stages: hematopoietic stem cells (HSCs), progenitor cells (HPCs), and granulocytes somatic cells are more efficient than adult stem cells for cloning by somatic cell nuclear transfer
Since the creation of Dolly, the first sheep cloned via somatic cell nuclear transfer (SCNT), in 1997, more than a dozen species of mammals have been cloned using this technology. One hypothesis for the limited success of cloning via SCNT (1-5%) is that the clones are likely derived from adult stem...
ORGANISM(S): Mus musculus 
2008-06-14 | E-GEOD-5677 | biostudies-arrayexpress
TranscriptomicsGene expression profile of microdissected mucinous ovarian tumors
Gene expression profile of 8 mucinous borderline ovarian tumors and 9 mucinous ovarian carcinomas. Frozen tumor samples were laser-capture microdissected for their epithelial component. RNA was extracted. Gene expression profiling was completed using Affymetrix U133 Plus 2.0 oligonucleotide microarr...
ORGANISM(S): Homo sapiens 
2018-06-28 | E-MTAB-6844 | biostudies-arrayexpress
UnknownBlinatumomab in Standard-Risk B-Cell Acute Lymphoblastic Leukemia in Children.
Not available
S-EPMC11864901 | biostudies-literature
UnknownPOLR1A variants underlie phenotypic heterogeneity in craniofacial, neural, and cardiac anomalies.
Not available
S-EPMC10183370 | biostudies-literature
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