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Protein synthesis and autophagic degradation are regulated in an opposite manner by mammalian target of rapamycin (mTOR), whereas under certain conditions it would be beneficial if they occured in unison to handle rapid protein turnover. We observed a distinct cellular compartment at the trans-side ...
ORGANISM(S): Homo sapiens 
In this study we adopt a chemical genetics system to evaluate whether auto-deubiquitylation would make DUBs poor substrates for targeted protein degradation.
ORGANISM(S): Homo Sapiens 
2025-11-29 | PXD071411 |
Guisoni2016 - Cis-regulatory system (CRS) can drive sustained oscillations This model is described in the article: Promoters Architecture-Based Mechanism for Noise-Induced Oscillations in a Single-Gene Circuit. Guisoni N, Monteoliva D, Diambra L. PLoS ONE 2016; 11(3): e015...
2016-11-03 | MODEL1611030000 | BioModels
Shimoni2009 - Escherichia Coli SOS Simple model, involving only the basic components of the circuit, sufficient to explain the peaks in the promoter activities of recA and lexA. This model is described in the article: Stochastic...
2005-01-01 | MODEL2937159804 | BioModels
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