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Autoinflammation with enhanced type I interferon signaling due to DNASE2 mutations
In humans, microbial nucleic acid recognition serves as the major stimulus to an antiviral response, implying a requirement for cellular mechanisms to limit misrepresentation of self nucleic acids as non-self and the subsequent induction of type I interferon-mediated autoinflammation. This RNA-seq s...
ORGANISM(S): Homo sapiens 
Cellular spermine controls autoinflammation by targeting JAK1 to restrain cytokine response
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