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ProteomicsMammalian hybrid pre-autophagosomal structure HyPAS generates autophagosomes
The biogenesis of mammalian autophagosomes remains to be fully defined. Here we used cellular and in vitro membrane fusion analyses to show that autophagosomes are formed from a hitherto unappreciated hybrid membrane compartment. The autophagic precursors emerge through fusion of FIP200 vesicles, de...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-07-16 | MSV000087840 | MassIVE
UnknownMammalian ATG8 proteins maintain autophagosomal membrane integrity through ESCRTs.
Not available
S-EPMC10350836 | biostudies-literature
UnknownDrosophila Golgi membrane protein Ema promotes autophagosomal growth and function.
Not available
S-EPMC3344964 | biostudies-literature
UnknownReconstitution of autophagosomal membrane tethering reveals that Atg11 can bind and cluster vesicles on cargo mimetics.
Not available
S-EPMC10769207 | biostudies-literature
UnknownPlasma membrane contributes to the formation of pre-autophagosomal structures.
Not available
S-EPMC2923063 | biostudies-literature
UnknownCOPII vesicles contribute to autophagosomal membranes.
Not available
S-EPMC6504894 | biostudies-literature
UnknownArabidopsis ORP2A mediates ER-autophagosomal membrane contact sites and regulates PI3P in plant autophagy.
Not available
S-EPMC9618059 | biostudies-literature
UnknownMammalian hybrid pre-autophagosomal structure HyPAS generates autophagosomes.
Not available
S-EPMC8616855 | biostudies-literature
UnknownWHAMM functions in kidney reabsorption and polymerizes actin to promote autophagosomal membrane closure and cargo sequestration.
Not available
S-EPMC11238085 | biostudies-literature
UnknownRab32 family proteins regulate autophagosomal components recycling.
Not available
S-EPMC10849918 | biostudies-literature
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