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TranscriptomicsTranscription profiling of human nevoid basal cell carcinoma syndrome primary fibroblasts with non-sense or miss-sense mutations in the tumor supressor gene PTCH1
Mutations in the tumor suppressor gene PTCH1 are responsible for Gorlin syndrome, or nevoid basal cell carcinoma syndrome (NBCCS). NBCCS causes predisposition to basal cell carcinoma (BCC), the commonest cancer in adult human. In the general population BCC develop almost exclusively in sun-exposed a...
ORGANISM(S): Homo sapiens 
2009-03-19 | E-TABM-549 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human TRAIL-resistant metastatic vs primary TRAIL-sensitive melanoma cells
T1 and G1 are the two melanoma cell lines, established from primary tumor (T1) and lymph node metastases (G1) of a 77 years old male patient. While G1 cells were resistant to TRAIL (TNF-related apoptosis-inducing ligand) mediated cell death, T1 cells exhibited a high dose- and time-dependent sensiti...
ORGANISM(S): Homo sapiens 
2006-01-01 | E-MEXP-247 | biostudies-arrayexpress
UnknownIntegrated pathway and epistasis analysis reveals interactive effect of genetic variants at TERF1 and AFAP1L2 loci on melanoma risk.
Not available
S-EPMC4566921 | biostudies-literature
UnknownA comprehensive genome-wide analysis of melanoma Breslow thickness identifies interaction between CDC42 and SCIN genetic variants.
Not available
S-EPMC5116391 | biostudies-literature
UnknownTranscription profiling of human TRAIL-resistant metastatic vs primary TRAIL-sensitive melanoma cells
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-MEXP-247 | biostudies-other
UnknownIL4-induced gene 1 promotes tumor growth by shaping the immune microenvironment in melanoma.
Not available
S-EPMC5384381 | biostudies-literature
UnknownSorafenib in advanced melanoma: a critical role for pharmacokinetics?
Not available
S-EPMC3405224 | biostudies-literature
UnknownDistinct merkel cell polyomavirus molecular features in tumour and non tumour specimens from patients with merkel cell carcinoma.
Not available
S-EPMC2928786 | biostudies-literature
UnknownBasal Cell Carcinoma in Gorlin's Patients: a Matter of Fibroblasts-Led Protumoral Microenvironment?
Not available
S-EPMC4687848 | biostudies-literature
UnknownCharacterization of the Microenvironment in Positive and Negative Sentinel Lymph Nodes from Melanoma Patients.
Not available
S-EPMC4517810 | biostudies-literature
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